PET Imaging of CXCR4 Receptors in Cancer by a New Optimized Ligand

被引:157
|
作者
Demmer, Oliver [1 ,2 ]
Gourni, Eleni [3 ]
Schumacher, Udo [4 ]
Kessler, Horst [1 ,2 ,5 ]
Wester, Hans-Juergen [3 ]
机构
[1] Tech Univ Munich, Inst Adv Study, Dept Chem, D-85748 Garching, Germany
[2] Tech Univ Munich, Ctr Integrated Prot Sci, Dept Chem, D-85748 Garching, Germany
[3] Tech Univ Munich, Lehrstuhl Pharmazeut Radiochem, D-85748 Garching, Germany
[4] Univ Klinikum Hamburg Eppendorf, Inst Anat Expt Morphol 2, D-20246 Hamburg, Germany
[5] King Abdulaziz Univ, Fac Sci, Dept Chem, Jeddah 21589, Saudi Arabia
关键词
CXCR4; DOTA; imaging agents; peptides; positron emission tomography; tracers; CHEMOKINE RECEPTOR; PERSONALIZED MEDICINE; HIGHLY POTENT; IN-VIVO; PEPTIDE; ANTAGONISTS; EXPRESSION; INHIBITOR; DISCOVERY; ONCOLOGY;
D O I
10.1002/cmdc.201100320
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
[No abstract available]
引用
收藏
页码:1789 / 1791
页数:3
相关论文
共 50 条
  • [41] Advances in PET Imaging of the CXCR4 Receptor: [68Ga]Ga-PentixaFor
    Lindenberg, Liza
    Ahlman, Mark
    Lin, Frank
    Mena, Esther
    Choyke, Peter
    SEMINARS IN NUCLEAR MEDICINE, 2024, 54 (01) : 163 - 170
  • [42] In vivo imaging of chemokine receptor CXCR4 expression by PET/MRI in patients with myeloid malignancies
    Herhaus, P.
    Philipp-Abbrederis, K.
    Habringer, S.
    Vag, T.
    Hoellein, A.
    Gerngross, C.
    Mueller-Thomas, C.
    Schwamborn, K.
    Peschel, C.
    Schwaiger, M.
    Wester, H. -J
    Verbeek, M.
    Goetze, K.
    Keller, U.
    Oncology Research and Treatment, 2015, 38 : 215 - 215
  • [43] Multimodality Imaging of CXCR4 in Cancer: Current Status towards Clinical Translation
    Nayak, T. R.
    Hong, H.
    Zhang, Y.
    Cai, W.
    CURRENT MOLECULAR MEDICINE, 2013, 13 (10) : 1538 - 1548
  • [44] Expression of the CXCR4 and CCR7 chemokine receptors in human endometrial cancer
    Kodama, J.
    Hasengaowa
    Seki, N.
    Kusumoto, T.
    Hiramatsu, Y.
    EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 2007, 28 (05) : 370 - 375
  • [45] Imaging of the chemokine receptor CXCR4 in prostate cancer patients using 68Ga-NOTA-NFB PET/CT
    Liu, Daliang
    Ma, Xiaowei
    Zhang, Mingru
    Li, Guiyu
    Wang, Jing
    Wang, Shengjun
    JOURNAL OF NUCLEAR MEDICINE, 2017, 58
  • [46] PET imaging targeting CXCR4 has the potential to distinguish different molecular subtypes of Small Cell Lung Cancer Tumors
    Luo, Yuxi
    Pei, Jinli
    Liu, Jie
    Yu, Jinming
    JOURNAL OF NUCLEAR MEDICINE, 2024, 65
  • [47] A synthetic bivalent ligand of CXCR4 inhibits HIV infection
    Xu, Yan
    Duggineni, Srinivas
    Espitia, Stephen
    Richman, Douglas D.
    An, Jing
    Huang, Ziwei
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2013, 435 (04) : 646 - 650
  • [48] CXCR7, CXCR4, and Their Ligand Expression Profile in Traumatic Brain Injury
    Mousessian, Adaliana Sorg
    Nunes da Silva, Clarisse Pereira
    Oba-Shinjo, Sueli Mieko
    Kolias, Angelos G.
    Paiva, Wellingson Silva
    Nagahashi Marie, Suely Kazue
    WORLD NEUROSURGERY, 2021, 147 : E16 - E24
  • [49] 68Ga-Pentixafor PET/CT Imaging Targeting CXCR4 chemokine receptors : The First Clinical Experience in Lung carcinoma subtypes
    Watts, A.
    Singh, B.
    Chutani, S.
    Dhanota, N.
    Singh, H.
    Basher, R.
    Bal, A.
    Kapoor, R.
    Arora, S. K.
    Wester, H. J.
    Mittal, B. R.
    Behera, D.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2017, 44 : S162 - S162
  • [50] Ligand binding characteristics of CXCR4 incorporated into paramagnetic proteoliposomes
    Babcock, GJ
    Mirzabekov, T
    Wojtowicz, W
    Sodroski, J
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (42) : 38433 - 38440