PET Imaging of CXCR4 Receptors in Cancer by a New Optimized Ligand

被引：157
|
作者：
Demmer, Oliver [1 ,2 ]
Gourni, Eleni [3 ]
Schumacher, Udo [4 ]
Kessler, Horst [1 ,2 ,5 ]
Wester, Hans-Juergen [3 ]
机构：
[1] Tech Univ Munich, Inst Adv Study, Dept Chem, D-85748 Garching, Germany
[2] Tech Univ Munich, Ctr Integrated Prot Sci, Dept Chem, D-85748 Garching, Germany
[3] Tech Univ Munich, Lehrstuhl Pharmazeut Radiochem, D-85748 Garching, Germany
[4] Univ Klinikum Hamburg Eppendorf, Inst Anat Expt Morphol 2, D-20246 Hamburg, Germany
[5] King Abdulaziz Univ, Fac Sci, Dept Chem, Jeddah 21589, Saudi Arabia
来源：
CHEMMEDCHEM | 2011年 / 6卷 / 10期
关键词：
CXCR4; DOTA; imaging agents; peptides; positron emission tomography; tracers; CHEMOKINE RECEPTOR; PERSONALIZED MEDICINE; HIGHLY POTENT; IN-VIVO; PEPTIDE; ANTAGONISTS; EXPRESSION; INHIBITOR; DISCOVERY; ONCOLOGY;
D O I：
10.1002/cmdc.201100320
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：1789 / 1791
页数：3
相关论文
共 50 条
  • [21] PET imaging of chemokine receptor CXCR4 in patients with primary and recurrent breast carcinoma
    Tibor Vag
    Katja Steiger
    Andreas Rossmann
    Ulrich Keller
    Aurelia Noske
    Peter Herhaus
    Johannes Ettl
    Markus Niemeyer
    Hans-Jürgen Wester
    Markus Schwaiger
    EJNMMI Research, 8
  • [22] Imaging CXCR4 expression in orthotopic and metastatic models of breast cancer
    Nimmagadda, Sridhar
    Pullambhatla, Mrudula
    Fox, James
    Green, Gilbert
    Pomper, Martin
    JOURNAL OF NUCLEAR MEDICINE, 2009, 50
  • [23] PET imaging of CXCR4 using copper-64 labeled peptide antagonist
    Jacobson, Orit
    Weiss, Ido D.
    Szajek, Lawrence P.
    Niu, Gang
    Ma, Ying
    Kiesewetter, Dale O.
    Farber, Joshua M.
    Chen, Xiaoyuan
    THERANOSTICS, 2011, 1 : 251 - 262
  • [24] Near-infrared molecular imaging of tumors via chemokine receptors CXCR4 and CXCR7
    Manuela Meincke
    Sanjay Tiwari
    Kirsten Hattermann
    Holger Kalthoff
    Rolf Mentlein
    Clinical & Experimental Metastasis, 2011, 28 : 713 - 720
  • [25] Near-infrared molecular imaging of tumors via chemokine receptors CXCR4 and CXCR7
    Meincke, Manuela
    Tiwari, Sanjay
    Hattermann, Kirsten
    Kalthoff, Holger
    Mentlein, Rolf
    CLINICAL & EXPERIMENTAL METASTASIS, 2011, 28 (08) : 713 - 720
  • [26] Colorectal Cancer: The Contribution of CXCL12 and Its Receptors CXCR4 and CXCR7
    Goita, Aissata Aimee
    Guenot, Dominique
    CANCERS, 2022, 14 (07)
  • [27] New macrocyclic imaging agents for targeting chemokine receptor CXCR4
    Poty, S.
    Desogere, P.
    Nicholson, K.
    Nigam, S.
    Goze, C.
    Boschetti, F.
    Maecke, H.
    Archibald, S.
    Denat, F.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2013, 40 : S285 - S285
  • [28] Imaging agents for the chemokine receptor 4 (CXCR4)
    Kuil, Joeri
    Buckle, Tessa
    van Leeuwen, Fijs W. B.
    CHEMICAL SOCIETY REVIEWS, 2012, 41 (15) : 5239 - 5261
  • [29] Ligand selectivity of a synthetic CXCR4 mimetic peptide
    Gross, Andrea
    Brox, Regine
    Damm, Dominik
    Tschammer, Nuska
    Schmidt, Barbara
    Eichler, Jutta
    BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 23 (14) : 4050 - 4055
  • [30] The Intricate Role of CXCR4 in Cancer
    Chatterjee, Samit
    Azad, Babak Behnam
    Nimmagadda, Sridhar
    EMERGING APPLICATIONS OF MOLECULAR IMAGING TO ONCOLOGY, 2014, 124 : 31 - 82
12345