PET Imaging of CXCR4 Receptors in Cancer by a New Optimized Ligand

被引:157
|
作者
Demmer, Oliver [1 ,2 ]
Gourni, Eleni [3 ]
Schumacher, Udo [4 ]
Kessler, Horst [1 ,2 ,5 ]
Wester, Hans-Juergen [3 ]
机构
[1] Tech Univ Munich, Inst Adv Study, Dept Chem, D-85748 Garching, Germany
[2] Tech Univ Munich, Ctr Integrated Prot Sci, Dept Chem, D-85748 Garching, Germany
[3] Tech Univ Munich, Lehrstuhl Pharmazeut Radiochem, D-85748 Garching, Germany
[4] Univ Klinikum Hamburg Eppendorf, Inst Anat Expt Morphol 2, D-20246 Hamburg, Germany
[5] King Abdulaziz Univ, Fac Sci, Dept Chem, Jeddah 21589, Saudi Arabia
关键词
CXCR4; DOTA; imaging agents; peptides; positron emission tomography; tracers; CHEMOKINE RECEPTOR; PERSONALIZED MEDICINE; HIGHLY POTENT; IN-VIVO; PEPTIDE; ANTAGONISTS; EXPRESSION; INHIBITOR; DISCOVERY; ONCOLOGY;
D O I
10.1002/cmdc.201100320
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
[No abstract available]
引用
收藏
页码:1789 / 1791
页数:3
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