Syntheses and spectral properties of unsymmetrically 3,5-disubstituted 2,6-dimethyl-1,4-dihydropyridines

被引：12

作者：

Ilavsky, D

Milata, V

机构：

[1] Department of Organic Chemistry, Slovak Technical University

来源：

COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS | 1996年 / 61卷 / 08期

关键词：

1,4-dihydropyridines, alkylation; Hantzsch synthesis;

D O I：

10.1135/cccc19961233

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Unsymmetrically 3,5-disubstituted 4-(5-X-2-furyl)-2,6-dimethyl-1,4-dihydropyridines (where X = H, Br, NO2) have been synthesized and characterized by spectral methods (IR, UV, H-1 NMR and MS). The modified Hantzsch method made it possible to prepare the title compounds as well as their N-alkylated derivatives. The paper also describes the N-alkylation of sodium salts of substituted 1,4-dihydropyridines using the phase-transfer catalysis.

引用

页码：1233 / 1243

页数：11

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