Syntheses and spectral properties of unsymmetrically 3,5-disubstituted 2,6-dimethyl-1,4-dihydropyridines

被引：12
|
作者：
Ilavsky, D
Milata, V
机构：
[1] Department of Organic Chemistry, Slovak Technical University
来源：
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS | 1996年 / 61卷 / 08期
关键词：
1,4-dihydropyridines, alkylation; Hantzsch synthesis;
D O I：
10.1135/cccc19961233
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Unsymmetrically 3,5-disubstituted 4-(5-X-2-furyl)-2,6-dimethyl-1,4-dihydropyridines (where X = H, Br, NO2) have been synthesized and characterized by spectral methods (IR, UV, H-1 NMR and MS). The modified Hantzsch method made it possible to prepare the title compounds as well as their N-alkylated derivatives. The paper also describes the N-alkylation of sodium salts of substituted 1,4-dihydropyridines using the phase-transfer catalysis.
引用
收藏
页码：1233 / 1243
页数：11
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