One-pot synthesis of optically active tetramic acids from amino acids mediated by 1-hydroxybenzotriazole

被引:1
|
作者
Athanasellis, G [1 ]
Gavrielatos, E [1 ]
Igglessi-Markopoulou, O [1 ]
机构
[1] Natl Tech Univ Athens, Dept Chem Engn, Organ Chem Lab, GR-15773 Athens, Greece
关键词
tetramic acids; 1-hydroxybenzotriazole; natural products; amino acids;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel synthesis of chiral 3-ethoxycarbonyl-5-substituted tetramic acids in moderate yields (45-75 %) is reported. HPLC analysis of these tetramic acids shows very good enantiomeric excesses (82-98 %).
引用
收藏
页码:1653 / 1655
页数:3
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