Simple microdilution test for detection of metallo-β-lactamase production in Pseudomonas aeruginosa

被引：70

作者：

Migliavacca, R

Docquier, JD

Mugnaioli, C

Amicosante, G

Daturi, R

Lee, KW

Rossolini, GM

Pagani, L

机构：

[1] Univ Pavia, Sez Nucribuik, Dipartimento Sci Morfol Eidol & Clin, I-27100 Pavia, Italy

[2] IRCCS S Matteo, Serv Anal Microbiol, I-27100 Pavia, Italy

[3] Univ Siena, Dipartimento Biol Mol, Sez Microbiol, I-53100 Siena, Italy

[4] Univ Aquila, Dipartimento Sci & Tecnol BIomed, I-67100 Laquila, Italy

[5] Yonsei Univ, Coll Med, Dept Clin Pathol, Seoul 120749, South Korea

[6] Yonsei Univ, Coll Med, Res Inst Bacterial Resistance, Seoul 120749, South Korea

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2002年 / 40卷 / 11期

关键词：

D O I：

10.1128/JCM.40.11.4388-4390.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A microdilution test measuring imipenem MICs in the presence or absence of a mixture of EDTA plus 1,10-phenanthroline was developed and tested on 190 Pseudomonas aeruginosa isolates, including 18VIM- and 4 IMP-type metallo-beta-lactamase (MBL) producers. The chelator mixture reduced by fourfold or more the imipenem MICs for MBL producers, while a lower effect or no effect was usually observed with MBL nonproducers.

引用

页码：4388 / 4390

页数：3

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