Synthesis of New Tetrazole Derivatives and Their Biological Evaluation

被引：15
|
作者：
Soliman, H. A. [1 ]
Kalmouch, A. [2 ]
Awad, H. M. [3 ]
Wahed, N. A. M. Abdel [4 ]
机构：
[1] Natl Res Ctr, Photochem Dept, Cairo 12622, Egypt
[2] Natl Res Ctr, Peptide Chem Dept, Cairo 12622, Egypt
[3] Natl Res Ctr, Tanning Mat & Leather Technol Dept, Cairo 12622, Egypt
[4] Natl Res Ctr, Chem Nat & Microbial Prod Dept, Cairo 12622, Egypt
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2018年 / 88卷 / 08期
关键词：
tetrachlorosilane; 1,5-disubstituted tetrazoles; mild conditions; anticancer activity; anti-microbial activity; ANTIOXIDANT; CHEMISTRY;
D O I：
10.1134/S1070363218080273
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An operationally simple and efficient method of synthesis of novel 1,5-disubstituted tetrazoles with high yields from easily accessible 2-(2-benzamido-3-arylacrylamido)acetate under mild conditions is developed. Anticancer and anti-microbial tests of the new tetrazole derivatives have been carried out.
引用
收藏
页码：1726 / 1733
页数：8
相关论文
共 50 条
  • [41] Synthesis and biological evaluation of new coumarin derivatives as cytotoxic agents
    Ragab, Fatma A.
    Eissa, Amal A. M.
    Fahim, Samar H.
    Salem, Mohammad A.
    Gamal, Mona A.
    Nissan, Yassin M.
    ARCHIV DER PHARMAZIE, 2021, 354 (08)
  • [42] Synthesis, crystal structures and biological evaluation of new pyridazine derivatives
    Singh, Bholey
    Bhatia, Rohit
    Pani, Balaram
    Gupta, Deepak
    JOURNAL OF MOLECULAR STRUCTURE, 2020, 1200
  • [43] Synthesis, Characterization and Biological Evaluation of Some New Pyrazoline Derivatives
    Jain, Dinesh Kumar
    Bhadoriya, Upendra
    Lodhi, Jawahar Lal
    ASIAN JOURNAL OF CHEMISTRY, 2013, 25 (03) : 1387 - 1390
  • [44] Synthesis and Biological Evaluation of New Bischromone Derivatives with Antiproliferative Activity
    Szulawska-Mroczek, Agata
    Szumilak, Marta
    Szczesio, Malgorzata
    Olczak, Andrzej
    Nazarski, Ryszard B.
    Lewgowd, Wieslawa
    Czyz, Malgorzata
    Stanczak, Andrzej
    ARCHIV DER PHARMAZIE, 2013, 346 (01) : 34 - 43
  • [45] Synthesis and biological evaluation of new biphenyl ether and thiazine derivatives
    Udupi, RH
    Bhat, AR
    Jacob, J
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2005, 15 (01) : 89 - 90
  • [46] SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW PYRAZOLINYL DERIVATIVES OF SYNTHETIC BIBENZYL
    Dwivedi, Smriti
    Shukla, Pavan K.
    Siddiqui, I. R.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2015, 25 (02) : 185 - 188
  • [47] Synthesis, Characterization and Biological Evaluation of Some New Isoxazoline Derivatives
    Jain, Dinesh K.
    Goyal, Neeraj
    Bhadoriya, Upendra
    ASIAN JOURNAL OF CHEMISTRY, 2013, 25 (02) : 789 - 792
  • [48] Synthesis and Biological Evaluation of New Pleuromutilin Derivatives as Antibacterial Agents
    Shang, Ruo-Feng
    Wang, Guan-Hua
    Xu, Xi-Ming
    Liu, Si-Jie
    Zhang, Chao
    Yi, Yun-Peng
    Liang, Jian-Ping
    Liu, Yu
    MOLECULES, 2014, 19 (11) : 19050 - 19065
  • [49] New benzimidazole derivatives: Design, synthesis, docking, and biological evaluation
    Obaid, Rami J.
    ARABIAN JOURNAL OF CHEMISTRY, 2023, 16 (02)
  • [50] Synthesis and biological evaluation of some new fused quinazoline derivatives
    Ibrahim, SS
    AbdelHalim, AM
    Gabr, Y
    ElEdfawy, S
    AbdelRahman, RM
    JOURNAL OF CHEMICAL RESEARCH-S, 1997, (05): : 154 - 155
12345