Synthesis and biological evaluation of some new fused quinazoline derivatives

被引：31
|
作者：
Ibrahim, SS [1 ]
AbdelHalim, AM [1 ]
Gabr, Y [1 ]
ElEdfawy, S [1 ]
AbdelRahman, RM [1 ]
机构：
[1] AIN SHAMS UNIV,FAC EDUC,DEPT CHEM,CAIRO,EGYPT
来源：
JOURNAL OF CHEMICAL RESEARCH-S | 1997年 / 05期
关键词：
D O I：
10.1039/a600184j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report that biologically active fused quinazolines have been synthesized via treatment of 3-(N-acyl/aroylamino)quinazolin-4(3H)-ones (2) with various nucleophilic reagents; some of the products showed moderate antibacterial activity.
引用
收藏
页码：154 / 155
页数：2
相关论文
共 50 条
  • [1] Synthesis and biological activities of some new fully fused quinazoline derivatives
    Ibrahim, SS
    Abdel-Halim, AM
    Gabr, Y
    El-Edfawy, S
    Abdel-Raman, RM
    [J]. INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1998, 37 (01): : 62 - 67
  • [2] SYNTHESIS AND ANTIHYPERTENSIVE ACTIVITY OF SOME FUSED QUINAZOLINE DERIVATIVES
    LIU, KC
    CHERN, JW
    [J]. HETEROCYCLES, 1984, 21 : 503 - 503
  • [3] Synthesis and biological evaluation of some quinazoline derivatives as antitumor and antiviral agents
    El-Sherbeny, MA
    Gineinah, MM
    Nasr, MN
    El-Shafeih, FS
    [J]. ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, 2003, 53 (03): : 206 - 213
  • [4] THE SYNTHESIS OF SOME QUINAZOLINE DERIVATIVES AND THEIR BIOLOGICAL PROPERTIES
    KARMINSKI, W
    KULICKA, J
    MIERNIK, J
    [J]. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES, 1983, 18 (4-5) : 599 - 610
  • [5] Synthesis of some new quinazoline derivatives
    Abdel-Hamide, SG
    [J]. INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2000, 10 (01) : 59 - 64
  • [6] Synthesis and biological evaluation of new quinazoline and cinnoline derivatives as potential atypical antipsychotics
    Alvarado, M
    Barceló, M
    Carro, L
    Masaguer, CF
    Raviña, E
    [J]. CHEMISTRY & BIODIVERSITY, 2006, 3 (01) : 106 - 117
  • [7] Synthesis and in vitro biological evaluation of novel quinazoline derivatives
    Zhang, Yaling
    Zhang, Ying
    Liu, Juan
    Chen, Li
    Zhao, Lijun
    Li, Baolin
    Wang, Wei
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27 (07) : 1584 - 1587
  • [8] DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NOVEL SUBSTITUTED QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS
    Ahmed, Marwa Farag
    Magdy, Naja
    [J]. ACTA POLONIAE PHARMACEUTICA, 2018, 75 (03): : 669 - 677
  • [9] Synthesis, biological evaluation, and computational studies of some novel quinazoline derivatives as anticancer agents
    Emami, Leila
    Khabnadideh, Soghra
    Faghih, Zahra
    Farahvasi, Farnoosh
    Zonobi, Fatemeh
    Gheshlaghi, Saman Zare
    Daili, Shadi
    Ebrahimi, Ali
    Faghih, Zeinab
    [J]. BMC CHEMISTRY, 2022, 16 (01)
  • [10] SYNTHESIS, CHARACTERISATION AND BIOLOGICAL EVALUATION OF SOME NOVEL QUINAZOLINE DERIVATIVES AS POTENTIAL ANTIMICROBIAL AGENTS
    Babu, K. Sudhakar
    Prabhakar, V.
    Ravindranath, L. K.
    Prasad, S. Shabhari
    Latha, J.
    [J]. HETEROCYCLIC LETTERS, 2016, 6 (03): : 427 - 441
12345