Synthesis of New Tetrazole Derivatives and Their Biological Evaluation

被引：15
|
作者：
Soliman, H. A. [1 ]
Kalmouch, A. [2 ]
Awad, H. M. [3 ]
Wahed, N. A. M. Abdel [4 ]
机构：
[1] Natl Res Ctr, Photochem Dept, Cairo 12622, Egypt
[2] Natl Res Ctr, Peptide Chem Dept, Cairo 12622, Egypt
[3] Natl Res Ctr, Tanning Mat & Leather Technol Dept, Cairo 12622, Egypt
[4] Natl Res Ctr, Chem Nat & Microbial Prod Dept, Cairo 12622, Egypt
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2018年 / 88卷 / 08期
关键词：
tetrachlorosilane; 1,5-disubstituted tetrazoles; mild conditions; anticancer activity; anti-microbial activity; ANTIOXIDANT; CHEMISTRY;
D O I：
10.1134/S1070363218080273
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An operationally simple and efficient method of synthesis of novel 1,5-disubstituted tetrazoles with high yields from easily accessible 2-(2-benzamido-3-arylacrylamido)acetate under mild conditions is developed. Anticancer and anti-microbial tests of the new tetrazole derivatives have been carried out.
引用
收藏
页码：1726 / 1733
页数：8
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