New bisabolane sesquiterpenoids from a marine-derived fungus Aspergillus sp isolated from the sponge Xestospongia testudinaria

被引：54

作者：

Sun, Ling-Ling ^{[1
]}

Shao, Chang-Lun ^{[1
]}

Chen, Jian-Feng ^{[3
]}

Guo, Zhi-Yong ^{[3
]}

Fu, Xiu-Mei ^{[1
]}

Chen, Min ^{[1
]}

Chen, Yi-Yan ^{[1
]}

Li, Rui ^{[1
]}

de Voogd, Nicole J. ^{[4
]}

She, Zhi-Gang ^{[2
]}

Lin, Yong-Cheng ^{[2
]}

Wang, Chang-Yun ^{[1
]}

机构：

[1] Ocean Univ China, Minist Educ China, Sch Med & Pharm, Key Lab Marine Drugs, Qingdao 266003, Peoples R China

[2] Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China

[3] China Three Gorges Univ, Coll Chem & Life Sci, Yichang 443002, Peoples R China

[4] Netherlands Ctr Biodivers Naturalis, NL-2300 RA Leiden, Netherlands

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2012年 / 22卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Phenolic bisabolane sesquiterpenoid; Marine-derived fungus; Aspergillus sp; Sponge; Cytotoxic activity; SYDONIC ACID; (+)-CURCUPHENOL; METABOLITES;

D O I：

10.1016/j.bmcl.2011.12.083

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three new phenolic bisabolane sesquiterpenoid dimers, disydonols A-C (1-3), and one known compound (S)-(+)-sydonol (4) were isolated from the fermentation broth of a marine-derived fungus Aspergillus sp., which was isolated from the sponge Xestospongia testudinaria collected from the South China Sea. Their structures were elucidated on the basis of comprehensive spectral analysis including 1D and 2D NMR spectra and HR-ESI-MS. These compounds were evaluated for cytotoxic activity against HepG-2 and Caski human tumour cell lines. Among them, compounds 1 and 3 exhibited cytotoxicity against the two cell lines. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：1326 / 1329

页数：4

共 50 条

[21] Drimane Sesquiterpenoids from the Fungus Aspergillus ustus Isolated from the Marine Sponge Suberites domuncula
Liu, Hongbing
Edrada-Ebel, RuAngelie
Ebel, Rainer
Wang, Yao
Schulz, Barbara
Draeger, Siegfried
Mueller, Werner E. G.
Wray, Victor
Lin, Wenhan
Proksch, Peter
JOURNAL OF NATURAL PRODUCTS, 2009, 72 (09): : 1585 - 1588
[22] Antifungal Drimane Sesquiterpenoids From a Marine-Derived Pleosporales sp. Fungus
Fei Cao
Dan Zhao
Xiao-Yue Chen
Xing-Di Liang
Wan Li
Hua-Jie Zhu
Chemistry of Natural Compounds, 2017, 53 : 1189 - 1191
[23] Sulfoxide-Containing Bisabolane Sesquiterpenoids with Antimicrobial and Nematicidal Activities from the Marine-Derived Fungus Aspergillus sydowii LW09
Yang, Xiao
Yu, Hongjia
Ren, Jinwei
Cai, Lei
Xu, Lijian
Liu, Ling
JOURNAL OF FUNGI, 2023, 9 (03)
[24] Antibacterial activity of marine bacteria isolated from sponge Xestospongia testudinaria from Sorong, Papua
Cita, Yatnita Parama
Suhermanto, Achmad
Radjasa, Ocky Karna
Sudharmono, Pratiwi
ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE, 2017, 7 (05) : 450 - 454
[25] Antibacterial activity of marine bacteria isolated from sponge Xestospongia testudinaria from Sorong,Papua
Yatnita Parama Cita
Achmad Suhermanto
Ocky Karna Radjasa
Pratiwi Sudharmono
Asian Pacific Journal of Tropical Biomedicine, 2017, (05) : 450 - 454
[26] Golmaenone, a new diketopiperazine alkaloid from the marine-derived fungus Aspergillus sp.
Li, Y
Li, XF
Kim, SK
Kang, JS
Choi, HD
Rho, JR
Son, BW
CHEMICAL & PHARMACEUTICAL BULLETIN, 2004, 52 (03) : 375 - 376
[27] Two new phenolic glucosides from marine-derived fungus Aspergillus sp.
Wen, Huiling
Zang, Yi
Zhu, Qianheng
Ouyang, Sheng
Luo, Juanjuan
Luo, Nianhua
Zhu, Hucheng
Zhang, Yonghui
NATURAL PRODUCT RESEARCH, 2022, 36 (13) : 3255 - 3261
[28] New mycotoxins from marine-derived fungus Aspergillus sp SCSGAF0093
Xu, Xinya
He, Fei
Zhang, Xiaoyong
Bao, Jie
Qi, Shuhua
FOOD AND CHEMICAL TOXICOLOGY, 2013, 53 : 46 - 51
[29] New Metabolites from the Marine-derived Fungus Aspergillus fumigatus
Afiyatullov, Shamil Sh
Zhuravleva, Olesya I.
Antonov, Alexandr S.
Kalinovsky, Anatoly I.
Pivkin, Michail V.
Menchinskaya, Ekaterina S.
Aminin, Dmitry L.
NATURAL PRODUCT COMMUNICATIONS, 2012, 7 (04) : 497 - 500
[30] A new diphenolic metabolite isolated from the marine-derived fungus Aspergillus niger 102
Zhang, Pan-Pan
Song, Shuang
Lang, Jia-Jia
Jia, Chun-Xiu
Yan, Su-Jun
Liu, Lan
Chen, Sen-Hua
Li, Jing
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 21 (08) : 813 - 819

← 1 2 3 4 5 →