A new diphenolic metabolite isolated from the marine-derived fungus Aspergillus niger 102

被引:4
|
作者
Zhang, Pan-Pan [1 ]
Song, Shuang [1 ]
Lang, Jia-Jia [3 ]
Jia, Chun-Xiu [3 ]
Yan, Su-Jun [3 ]
Liu, Lan [1 ,2 ]
Chen, Sen-Hua [1 ]
Li, Jing [1 ]
机构
[1] Sun Yat Sen Univ, Sch Marine Sci, Guangzhou 510006, Guangdong, Peoples R China
[2] Sun Yat Sen Univ, Key Lab Funct Mol Ocean Microorganisms, Dept Educ Guangdong Prov, Guangzhou 510006, Guangdong, Peoples R China
[3] Sun Yat Sen Univ, Sch Chem, Guangzhou 510006, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
Aspergillus niger; diphenolic; naptho-gamma-pyrones; NAPHTHO-GAMMA-PYRONES; TERREUS; BUTYROLACTONES;
D O I
10.1080/10286020.2018.1488830
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A new diphenolic derivative asperdiphenol A (1), along with nine known compounds (2-10), was isolated from the marine-derived fungus Aspergillus niger 102. Their structures were elucidated on the basis of spectroscopic analysis including NMR and MS spectrometry. Compound 1 was suggested to be a chiral mixture by the specific rotation and chiral HPLC. Compound 1 was evaluated for its anti-inflammatory, antibacterial, and cytotoxic activity. [GRAPHICS] .
引用
收藏
页码:813 / 819
页数:7
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