Triterpene glycosides from the aerial parts of Larrea tridentata

被引：24
|
作者：
Jitsuno, Maki [1 ]
Mimaki, Yoshihiro [1 ]
机构：
[1] Tokyo Univ Pharm & Life Sci, Sch Pharm, Tokyo 1920392, Japan
来源：
PHYTOCHEMISTRY | 2010年 / 71卷 / 17-18期
关键词：
Larrea tridentata; Zygophyllaceae; Triterpene glycosides; HL-60; cells; Cytotoxic activity; GUAIACUM-OFFICINALE; SAPONINS; LIGNANS; LEAVES; BULBS; BARK;
D O I：
10.1016/j.phytochem.2010.09.012
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Chemical study of the aerial parts of Larrea tridentata (Zygophyllaceae) resulted in the isolation of 25 triterpene glycosides 13 of which were previously unknown Their structures were determined on the basis of comprehensive spectroscopic analyses including 20 NMR spectroscopy and hydrolytic cleavage followed by chromatographic and spectroscopic analyses This is the first systematic phytochemical study of L. tridentata with attention paid to its triterpene glycoside constituents The isolated compounds were evaluated for their cytotoxic activity against HL-60 human promyelocytic leukemia cells (C) 2010 Elsevier Ltd All rights reserved
引用
收藏
页码：2157 / 2167
页数：11
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