Recent advance in the structural analysis of HIV-1 envelope protein

被引：1
|
作者：
Matsuda, Zene [1 ,2 ]
机构：
[1] Univ Tokyo, Inst Med Sci, Res Ctr Asian Infect Dis, Tokyo 1088639, Japan
[2] Chinese Acad Sci, Inst Biophys, Lab Struct Virol & Immunol, Beijing 100101, Peoples R China
来源：
SCIENCE CHINA-LIFE SCIENCES | 2015年 / 58卷 / 05期
关键词：
HIV-1; envelope glycoprotein; CryoEM; structure; membrane fusion; vaccine; DEPENDENT EPITOPE; MEMBRANE-FUSION; GLYCOPROTEIN; TRIMERS; GP41; ANTIBODIES; INFECTION; GENE; ENV;
D O I：
10.1007/s11427-015-4852-1
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Human immunodeficiency virus type I (HIV-1), a causative agent of AIDS, is affecting today more than 35 millions of people worldwide. The advance of anti-HIV chemotherapy has made AIDS a chronic non-fatal disease in resourceful countries. Long-awaited anti-HIV-1 vaccine is still not with us yet; however, great progress in structural analyses of the envelope protein of HIV-1 in recent years starts to shed light on rational intervention targeted at the envelope protein, as will be reviewed in this article.
引用
收藏
页码：420 / 424
页数：5
相关论文
共 50 条
  • [1] Recent advance in the structural analysis of HIV-1 envelope protein
    MATSUDA Zene
    Science China(Life Sciences), 2015, 58 (05) : 420 - 424
  • [2] Recent advance in the structural analysis of HIV-1 envelope protein
    Zene Matsuda
    Science China Life Sciences, 2015, 58 : 420 - 424
  • [3] Recent advance in the structural analysis of HIV-1 envelope protein
    MATSUDA Zene
    Science China Life Sciences, 2015, (05) : 420 - 424
  • [4] The HIV-1 Antisense Protein ASP is s Structural Protein of the Viral Envelope
    Affram, Yvonne
    Zapata, Juan Carlos
    Zhou, Wei
    Pazgier, Marzena
    Iglesias-Ussel, Maria
    Ray, Krishanu
    Latinovic, Olga
    Romerio, Fabio
    JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2019, 81 : 79 - 79
  • [5] Recent Advances on the Use of Structural Biology for the Design of Novel Envelope Immunogens of HIV-1
    Xiang, Shi-Hua
    CURRENT HIV RESEARCH, 2013, 11 (06) : 464 - 472
  • [6] Molecular makeup of HIV-1 envelope protein
    Veljkovic, V
    Veljkovic, N
    Metlas, R
    INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2004, 23 (5-6) : 383 - 411
  • [7] STRUCTURAL-ANALYSIS OF THE HIV-1 ENVELOPE GLYCOPROTEIN GP120
    MOORE, JP
    THALI, M
    JAMESON, BA
    LEWIS, GK
    SATTENTAU, QJ
    SODROSKI, J
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1993, : 4 - 4
  • [8] FOLDING, OLIGOMERIZATION, AND PROCESSING OF THE HIV-1 ENVELOPE PROTEIN
    DOMS, RW
    EARL, PL
    MOSS, B
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 1991, 7 (02) : 196 - 197
  • [9] GLYCOSYLATION OF HIV-1 ENVELOPE PROTEIN - VACCINE CONSIDERATION
    LEE, TH
    JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1993, 6 (06): : 679 - 679
  • [10] Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein
    Piai, Alessandro
    Fu, Qingshan
    Cai, Yongfei
    Ghantous, Fadi
    Xiao, Tianshu
    Shaik, Md Munan
    Peng, Hanqin
    Rits-Volloch, Sophia
    Chen, Wen
    Seaman, Michael S.
    Chen, Bing
    Chou, James J.
    NATURE COMMUNICATIONS, 2020, 11 (01)
12345