Molecular makeup of HIV-1 envelope protein

被引：6
|
作者：
Veljkovic, V
Veljkovic, N
Metlas, R
机构：
[1] Inst Nucl Sci VINCA, Ctr Multidisciplinary Res, YU-11001 Belgrade, Serbia
[2] Diapharm Ltd, Guernsey, Channel Islands, England
来源：
INTERNATIONAL REVIEWS OF IMMUNOLOGY | 2004年 / 23卷 / 5-6期
关键词：
HIV-1; gp120; immunoglobulin; VIP; homology; molecular mimicry;
D O I：
10.1080/08830180490432749
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A broad range of structural, functional, and immunological similarities between HIV-1 gp120 and human proteins, especially those participating in immune responses, highlight gp120 as a pleiotropic protein that can in different ways affect many important functions of the human immune system. Here we described some of these properties of HIV-1 gp120 that represent the main obstacle in the development of effective and safe AIDS vaccine.
引用
收藏
页码：383 / 411
页数：29
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