Application of novel phosphine oxazoline ligands in asymmetric allylations of 4-acyloxy-2-pentene derivatives

被引：26
|
作者：
Burgess, K [1 ]
Porte, AM [1 ]
机构：
[1] Texas A&M Univ, Dept Chem, College Stn, TX 77842 USA
来源：
TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 14期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/S0957-4166(98)00230-4
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A library of novel phosphine oxazoline ligands 2 was tested in the asymmetric allylation of 4-acyloxy-2-pentenes 1. High throughput screening techniques were employed to accelerate this process. The data accumulated allowed the extent of asymmetric induction to be correlated with the ligand substituent R and ligand-to-metal ratios. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：2465 / 2469
页数：5
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