MEDI 511-Discovery of potent pyrrolidine BACE-1 inhibitors

被引：0

作者：

Iserloh, Ulrich ^{[1
]}

Pan, Jianping ^{[1
]}

Buevich, Alex ^{[1
]}

Chen, Xia ^{[1
]}

Cumming, Jared ^{[1
]}

Favreau, Len ^{[1
]}

Greenlee, William ^{[1
]}

Huang, Ying ^{[1
]}

Kennedy, Matthew ^{[1
]}

Kuvelkar, Reshma ^{[1
]}

McHugh, Nansie ^{[1
]}

Li, Guoqing ^{[1
]}

Parker, Eric M. ^{[1
]}

Strickland, Corey ^{[1
]}

Stamford, Andrew ^{[1
]}

Tucker, Greg ^{[1
]}

Voigt, Johannes ^{[1
]}

Wang, Lingyan ^{[1
]}

Wu, Yusheng ^{[1
]}

Zhang, Qi ^{[1
]}

Zhang, Lili ^{[1
]}

机构：

[1] Schering Plough Res Inst, Kenilworth, NJ 07033 USA

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 232卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

511-MEDI

引用

页数：1

共 50 条

[1] MEDI 513-Discovery of potent macrocyclic BACE-1 inhibitors
Li, Guoqing
Huang, Ying
Stamford, Andrew W.
Greenlee, William J.
Kennedy, Matthew
Chen, Xia
Kuvelkar, Reshma
Strickland, Corey
Voigt, Johannes
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232
[2] MEDI 510-Discovery of highly potent piperazine BACE-1 inhibitors
Huang, Ying
Chen, Xia
Greenlee, William
Kennedy, Matthew
Kuvelkar, Reshma
Li, Guoqing
Parker, Eric M.
Stamford, Andrew
Strickland, Corey
Voigt, Johannes
Zhang, Lili
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232
[3] Potent pyrrolidine- and piperidine-based BACE-1 inhibitors
Iserloh, U.
Wu, Y.
Cumming, J. N.
Pan, J.
Wang, L. Y.
Stamford, A. W.
Kennedy, M. E.
Kuvelkar, R.
Chen, X.
Parker, E. M.
Strickland, C.
Voigt, J.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (01) : 414 - 417
[4] MEDI 186-Discovery and optimization of acyl guanidines as novel BACE-1 inhibitors
Gerritz, Samuel W.
Shi, Shuhao
Zhai, Weixu
Zhu, Shirong
Thompson, Lorin A.
Toyn, Jeremy H.
Meredith, Jere E.
Good, Andrew C.
Muckelbauer, Jodi K.
Camac, Daniel M.
Dodd, Dharmpal S.
Cook, Lynda S.
Padmanabha, Ramesh
Albright, Charles F.
Sofia, Michael J.
Poss, Michael A.
Macor, John E.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 235
[5] Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors
Veenstra, Siem Jakob
Rueeger, Heinrich
Voegtle, Markus
Lueoend, Rainer
Holzer, Philipp
Hurth, Konstanze
Tintelnot-Blomley, Marina
Frederiksen, Mathias
Rondeau, Jean-Michel
Jacobson, Laura
Staufenbiel, Matthias
Neumann, Ulf
Machauer, Rainer
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28 (12) : 2195 - 2200
[6] MEDI 509-Discovery and development of novel BACE-1 inhibitors: Substituted piperidine analogs
Wu, Yusheng
Stamford, Andrew
Cumming, Jared
Iserloh, Ulrich
Greenlee, William
Kennedy, Matthew
Chen, Xia
Kuvelkar, Reshma
McHugh, Nansie
Voigt, Johannes
Strickland, Corey
Favreau, Leonard
Li, Cheng
Liu, TongTong
Chan, Tze-Ming
Osterman, Rebecca
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232
[7] MEDI 296-Pyrrolidines as conformationally constrained diaminopropanes: A versatile scaffold for potent inhibitors of BACE-1
Guernon, Jason M.
Thompson, Lorin A., III
Macor, John E.
Tebben, Andrew J.
Good, Andrew
Burton, Catherine R.
Barten, Donna M.
Marcinkeviciene, Jovita
Toyn, Jeremy H.
Albright, Charlie
Muckelbauer, Jodi K.
Camac, Daniel
Zvyaga, Tatyana
Grace, James
Lentz, Kimberly
Boy, Kenneth M.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 234
[8] Discovery of potent β-secretase (bace-1) inhibitors by the synthesis of isophthalamide-containing hybrids
Zhu, Yi-ping
Xiao, Kun
Yu, Hai-ping
Ma, Lan-ping
Xiong, Bing
Zhang, Hai-yan
Wang, Xin
Li, Jing-ya
Li, Jia
Shen, Jing-kang
ACTA PHARMACOLOGICA SINICA, 2009, 30 (02) : 259 - 269
[9] Discovery of potent β-secretase (bace-1) inhibitors by the synthesis of isophthalamide-containing hybrids
Yi-ping Zhu
Kun Xiao
Hai-ping Yu
Lan-ping Ma
Bing Xiong
Hai-yan Zhang
Xin Wang
Jing-ya Li
Jia Li
Jing-kang Shen
Acta Pharmacologica Sinica, 2009, 30 : 259 - 269
[10] Design and Synthesis of Potent and Selective BACE-1 Inhibitors
Bjorklund, Catarina
Oscarson, Stefan
Benkestock, Kurt
Borkakoti, Neera
Jansson, Katarina
Lindberg, Jimmy
Vrang, Lotta
Hallberg, Anders
Rosenquist, Asa
Samuelsson, Bertil
JOURNAL OF MEDICINAL CHEMISTRY, 2010, 53 (04) : 1458 - 1464

← 1 2 3 4 5 →