COVID-19 reinfection: the role of natural immunity, vaccines, and variants

被引：26

作者：

Sciscent, Bao Y. ^{[1
]}

Eisele, Caroline D. ^{[1
]}

Ho, Lisa ^{[1
]}

King, Steven D. ^{[1
]}

Jain, Rohit ^{[2
]}

Golamari, Reshma R. ^{[2
]}

机构：

[1] Penn State Univ, Coll Med, Hershey, PA USA

[2] Penn State Hlth Milton S Hershey Med Ctr, Dept Hosp Med, Hershey, PA 17033 USA

来源：

JOURNAL OF COMMUNITY HOSPITAL INTERNAL MEDICINE PERSPECTIVES | 2021年 / 11卷 / 06期

关键词：

COVID-19; reinfection; vaccination; immunity; SARS-CoV-2; SARS-COV-2; VACCINATION; PROTECTION;

D O I：

10.1080/20009666.2021.1974665

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The COVID-19 pandemic has altered innumerable lives. Although recent mass vaccinations offer a glimmer of hope, the rising death toll and new variants continue to dominate the current scenario. As we begin to understand more about SARS-CoV-2 infections, the territory of reinfections with COVID-19 remains unexplored. In this review, we will discuss several aspects of reinfection: (a) How is COVID-19 reinfection characterized? (b) Does prior literature differentiate between reinfection and reactivation? (c) What SARS-CoV-2 strains do the vaccines target and can they protect against new strains? Larger and longer timeline studies are needed to understand reinfection risks. With the ongoing distribution of the SARS-CoV-2 vaccines to provide protection, the understanding of the possibility for SARS-CoV-2 reinfection remains critical.

引用

页码：733 / 739

页数：7

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