COVID-19: IS REINFECTION POSSIBLE?

被引:9
|
作者
Cortez Costa, Arata Oliveira [1 ]
Aragao Neto, Humberto de Carvalho [1 ]
Lopes Nunes, Ana Paula [1 ]
de Castro, Ricardo Dias [1 ]
de Almeida, Reinaldo Nobrega [1 ]
机构
[1] Univ Fed Paraiba, Inst Drugs & Med Res, Psychopharmacol Lab, Joao Pessoa, Paraiba, Brazil
来源
EXCLI JOURNAL | 2021年 / 20卷
关键词
SARS-CoV-2; COVID-19; pandemic; reinfection; recurrence; recover; CLINICAL CHARACTERISTICS;
D O I
10.17179/excli2021-3383
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The COVID-19 pandemic has spread rapidly in many countries, overburdening health systems and causing numerous economic and social impacts. Most studies on the subject have focused on epidemiology, diagnosis, and treatment, however, there remains a scientific gap concerning the possibility of reinfection. The purpose of this bibliographic review is to gather information from studies aimed at this possibility, and to clarify what we know so far. It was found that in many situations cured patients are being released from hospitals, however, in some cases, the discharge criteria are not effective. Patients are presenting positive RT-PCR tests. There are several factors that might interfere so that patients cured of COVID-19 continue to test positive, and this would not necessarily represent a case of recurrence, as the test cannot differentiate the viral RNA from the complete virus, which alone is capable of causing the active infection. This review demonstrates that in order to rule out the possibility of COVID-19 reinfection in cured patients, more robust methods need to be adopted as criteria for both clinical discharge and post-hospital follow-up.
引用
收藏
页码:522 / 536
页数:15
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