The COVID-19 pandemic has spread rapidly in many countries, overburdening health systems and causing numerous economic and social impacts. Most studies on the subject have focused on epidemiology, diagnosis, and treatment, however, there remains a scientific gap concerning the possibility of reinfection. The purpose of this bibliographic review is to gather information from studies aimed at this possibility, and to clarify what we know so far. It was found that in many situations cured patients are being released from hospitals, however, in some cases, the discharge criteria are not effective. Patients are presenting positive RT-PCR tests. There are several factors that might interfere so that patients cured of COVID-19 continue to test positive, and this would not necessarily represent a case of recurrence, as the test cannot differentiate the viral RNA from the complete virus, which alone is capable of causing the active infection. This review demonstrates that in order to rule out the possibility of COVID-19 reinfection in cured patients, more robust methods need to be adopted as criteria for both clinical discharge and post-hospital follow-up.
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Legal Med Org, Legal Med Res Ctr, Tehran, IranACECR, Royan Inst Biotechnol, Cell Sci Res Ctr, Dept Cellular Biotechnol, Esfahan, Iran
Iravani, Omid
Ghaedi, Kamran
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Univ Isfahan, Dept Biol, Fac Sci, Div Cellular & Mol Biol, Esfahan, IranACECR, Royan Inst Biotechnol, Cell Sci Res Ctr, Dept Cellular Biotechnol, Esfahan, Iran
Ghaedi, Kamran
Forootan, Farzad S.
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Isfahan Univ Med Sci, Genome Med Genet Res Ctr, Esfahan, Iran
Legal Med Org, Legal Med Res Ctr, Tehran, IranACECR, Royan Inst Biotechnol, Cell Sci Res Ctr, Dept Cellular Biotechnol, Esfahan, Iran
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Univ Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, BrazilUniv Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, Brazil
Bonifacio, Livia Pimenta
Sulino Pereira, Ana Paula
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Univ Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, BrazilUniv Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, Brazil
Sulino Pereira, Ana Paula
de Almeida e Araujo, Daniel Cardoso
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Serv Vigilancia Epidemiol Municipal Ribeirao Pret, Ribeirao Preto, SP, BrazilUniv Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, Brazil
de Almeida e Araujo, Daniel Cardoso
Pasti Balbao, Viviane da Mata
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Serv Vigilancia Epidemiol Municipal Ribeirao Pret, Ribeirao Preto, SP, BrazilUniv Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, Brazil
Pasti Balbao, Viviane da Mata
Lopes da Fonseca, Benedito Antonio
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Univ Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, BrazilUniv Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, Brazil
Lopes da Fonseca, Benedito Antonio
Costa Passos, Afonso Dinis
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Univ Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, Brazil
Univ Sao Paulo, Fac Med Ribeirao Preto, Nucleo Vigilancia Epidemiol Hosp, Hosp Clin, Ribeirao Preto, SP, BrazilUniv Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, Brazil
Costa Passos, Afonso Dinis
Bellissimo-Rodrigues, Fernando
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Univ Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, Brazil
Univ Sao Paulo, Fac Med Ribeirao Preto, Nucleo Vigilancia Epidemiol Hosp, Hosp Clin, Ribeirao Preto, SP, BrazilUniv Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, Brazil
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Hebrew Univ Jerusalem, Infect Dis Unit, Sharee Zedek Med Ctr, Jerusalem, IsraelHebrew Univ Jerusalem, Infect Dis Unit, Sharee Zedek Med Ctr, Jerusalem, Israel
Ben-Chetrit, Eli
Ben-Chetrit, Eldad
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Hebrew Univ Jerusalem, Hadassah Med Ctr, Rheumatol Unit, Jerusalem, Israel
Hebrew Univ Jerusalem, Fac Med, Jerusalem, IsraelHebrew Univ Jerusalem, Infect Dis Unit, Sharee Zedek Med Ctr, Jerusalem, Israel