Palladium-catalyzed regio-selective oxidative C-H bond acylation of azoxybenzenes with alcohols

被引：24

作者：

Hou, Lekai ^{[1
]}

Chen, Xiangxiang ^{[1
]}

Li, Shuang ^{[1
]}

Cai, Suxian ^{[1
]}

Zhao, Yanxia ^{[1
]}

Sun, Meng ^{[1
]}

Yang, Xiao-Juan ^{[1
]}

机构：

[1] NW Univ Xian, Dept Chem & Mat Sci, Minist Educ, Key Lab Synthet & Nat Funct Mol Chem, Xian 710069, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2015年 / 13卷 / 14期

关键词：

O-METHYL OXIMES; DIRECT ARYLATION; DIRECTING GROUP; ACETANILIDES; ACTIVATION; ARYL; ALDEHYDES; FUNCTIONALIZATION; OLEFINATION; BENZAMIDES;

D O I：

10.1039/c5ob00089k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A palladium-catalyzed regio-selective acylation of C-H bonds of azoxybenzenes with alcohols was developed using tert-butyl hydroperoxide (TBHP) as an oxidant. Alcohol derivatives can act as effective acyl precursors in situ, which are less toxic, inexpensive, stable, and commercially available. These transformations proceeded smoothly and could tolerate a variety of functional groups.

引用

页码：4160 / 4164

页数：5

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