A Novel One-Pot Three-Component Reaction for Rapid Access of Arylidene 2-Aminoimidazolone Derivatives

被引：2

作者：

Hanif, Aansa ^{[1
]}

Sardar, Aniqa ^{[1
]}

Alazmi, Meshari ^{[2
]}

Tariq, Haniya ^{[1
]}

Emwas, Abdul-Hamid ^{[3
]}

Gao, Xin ^{[2
]}

Chotana, Ghayoor Abbas ^{[1
]}

Saleem, Rahman Shah Zaib ^{[1
]}

机构：

[1] Lahore Univ Management Sci, SBA Sch Sci & Engn, Dept Chem & Chem Engn, DHA, Opposite Sect U, Lahore 54792, Pakistan

[2] King Abdullah Univ Sci & Technol, Comp Elect & Math Sci & Engn Div, Thuwal 239556900, Saudi Arabia

[3] King Abdullah Univ Sci & Technol, Core Labs, Thuwal 239556900, Saudi Arabia

来源：

CHEMISTRYSELECT | 2019年 / 4卷 / 05期

关键词：

Arylidene; 2-aminoimidazolones; Combinatorial synthesis; Multicomponent reaction; Natural product derivatives; Three-component reaction; MARINE; HYMENIALDISINE; DEBROMOHYMENIALDISINE; PACLITAXEL; BINDING;

D O I：

10.1002/slct.201803409

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and convenient one-pot reaction for the synthesis of arylidene 2-aminoimidazolone derivatives from structurally diverse benzaldehydes, amines and 2-(methylthio)-1H-imidazol-4(5H)-one is described. The reaction offers flexibility of use of electron-rich and electron-deficient benzaldehydes and mono and di-substituted amines for the rapid development of combinatorial library.

引用

页码：1753 / 1756

页数：4

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