A Novel One-Pot Three-Component Reaction for Rapid Access of Arylidene 2-Aminoimidazolone Derivatives

被引：2
|
作者：
Hanif, Aansa [1 ]
Sardar, Aniqa [1 ]
Alazmi, Meshari [2 ]
Tariq, Haniya [1 ]
Emwas, Abdul-Hamid [3 ]
Gao, Xin [2 ]
Chotana, Ghayoor Abbas [1 ]
Saleem, Rahman Shah Zaib [1 ]
机构：
[1] Lahore Univ Management Sci, SBA Sch Sci & Engn, Dept Chem & Chem Engn, DHA, Opposite Sect U, Lahore 54792, Pakistan
[2] King Abdullah Univ Sci & Technol, Comp Elect & Math Sci & Engn Div, Thuwal 239556900, Saudi Arabia
[3] King Abdullah Univ Sci & Technol, Core Labs, Thuwal 239556900, Saudi Arabia
来源：
CHEMISTRYSELECT | 2019年 / 4卷 / 05期
关键词：
Arylidene; 2-aminoimidazolones; Combinatorial synthesis; Multicomponent reaction; Natural product derivatives; Three-component reaction; MARINE; HYMENIALDISINE; DEBROMOHYMENIALDISINE; PACLITAXEL; BINDING;
D O I：
10.1002/slct.201803409
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple and convenient one-pot reaction for the synthesis of arylidene 2-aminoimidazolone derivatives from structurally diverse benzaldehydes, amines and 2-(methylthio)-1H-imidazol-4(5H)-one is described. The reaction offers flexibility of use of electron-rich and electron-deficient benzaldehydes and mono and di-substituted amines for the rapid development of combinatorial library.
引用
收藏
页码：1753 / 1756
页数：4
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