Synthesis and Application of Silica Phenyl Sulfonic Acid as a Solid Acid Heterogeneous Catalyst for One-Pot Synthesis of 2-Aryl-1-arylmethyl-1H-1,3-benzimidazoles and Bis(indolyl)methanes in Water

被引：25

作者：

Veisi, Hojat ^{[1
]}

Sedrpoushan, Alireza ^{[2
,3
]}

Zolfigol, Mohammad Ali ^{[2
]}

Mohanazadeh, Farajollah ^{[3
]}

机构：

[1] Payame Noor Univ, Dept Chem, Tehran, Iran

[2] Bu Ali Sina Univ, Fac Chem, Hamadan 6517838683, Iran

[3] Iranian Res Org Sci & Technol, Dept Ind Chem, Tehran, Iran

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2011年 / 48卷 / 06期

关键词：

HIV-1; REVERSE-TRANSCRIPTASE; HIGHLY EFFICIENT SYNTHESIS; SOLVENT-FREE CONDITIONS; BENZIMIDAZOLE DERIVATIVES; CARBONYL-COMPOUNDS; IONIC LIQUID; SELECTIVE SYNTHESIS; BIOLOGICAL-ACTIVITY; ELECTROPHILIC SUBSTITUTION; NONNUCLEOSIDE INHIBITORS;

D O I：

10.1002/jhet.765

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Silica phenyl sulfonic acid (SPSA) was prepared and effectively used in the one-pot synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzimidazoles from o-phenylenediamine with aldehydes in water in the presence of tetrabutyl ammonium bromide with good to high yield. Also, SPSA was used as a catalyst for the synthesis of bis(indolyl)methanes in water.

引用

页码：1448 / 1454

页数：7

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