Synthesis and Application of Silica Phenyl Sulfonic Acid as a Solid Acid Heterogeneous Catalyst for One-Pot Synthesis of 2-Aryl-1-arylmethyl-1H-1,3-benzimidazoles and Bis(indolyl)methanes in Water

被引：25
|
作者：
Veisi, Hojat [1 ]
Sedrpoushan, Alireza [2 ,3 ]
Zolfigol, Mohammad Ali [2 ]
Mohanazadeh, Farajollah [3 ]
机构：
[1] Payame Noor Univ, Dept Chem, Tehran, Iran
[2] Bu Ali Sina Univ, Fac Chem, Hamadan 6517838683, Iran
[3] Iranian Res Org Sci & Technol, Dept Ind Chem, Tehran, Iran
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2011年 / 48卷 / 06期
关键词：
HIV-1; REVERSE-TRANSCRIPTASE; HIGHLY EFFICIENT SYNTHESIS; SOLVENT-FREE CONDITIONS; BENZIMIDAZOLE DERIVATIVES; CARBONYL-COMPOUNDS; IONIC LIQUID; SELECTIVE SYNTHESIS; BIOLOGICAL-ACTIVITY; ELECTROPHILIC SUBSTITUTION; NONNUCLEOSIDE INHIBITORS;
D O I：
10.1002/jhet.765
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Silica phenyl sulfonic acid (SPSA) was prepared and effectively used in the one-pot synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzimidazoles from o-phenylenediamine with aldehydes in water in the presence of tetrabutyl ammonium bromide with good to high yield. Also, SPSA was used as a catalyst for the synthesis of bis(indolyl)methanes in water.
引用
收藏
页码：1448 / 1454
页数：7
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