Silica sulfuric acid (SSA) as a solid acid heterogeneous catalyst for one-pot synthesis of substituted pyrroles under solvent-free conditions at room temperature

被引:112
|
作者
Veisi, Hojat
机构
[1] Department of Chemistry, Payame Noor University (PNU)
关键词
Silica sulfuric acid; Paal-Knorr reaction; Pyrroles; Solvent-free conditions; POLYSUBSTITUTED PYRROLES; BIS(INDOLYL)METHANES; FURANS; ROUTE;
D O I
10.1016/j.tetlet.2010.02.052
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A variety of N-substituted pyrroles have been synthesized by reacting gamma-diketones with amines, diamines or triamine in the presence of silica sulfuric acid (SSA) at room temperature under solvent-free conditions. The experiment protocol features simple operations, and the products are isolated in high to excellent yields (70-98%). (c) 2010 Elsevier Ltd. All rights reserved.
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页码:2109 / 2114
页数:6
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