Pd-Catalyzed Multiple C-H Functionalization to Construct Biologically Active Compounds from Aryl Aldoxime Ethers with Arenes

被引：54

作者：

Thirunavukkarasu, Vedhagiri S. ^{[1
]}

Cheng, Chien-Hong ^{[1
]}

机构：

[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu 30013, Taiwan

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2011年 / 17卷 / 52期

关键词：

C?H activation; cyclization; fluorenone; oxime ether; palladium; CROSS-COUPLING REACTIONS; ONE-POT SYNTHESIS; ORTHO-ARYLATION; BOND FUNCTIONALIZATION; ELECTRON-DEFICIENT; UNACTIVATED ARENES; SODIUM PERSULFATE; ACTIVATION; FLUORENONES; DERIVATIVES;

D O I：

10.1002/chem.201102996

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Functional fluorenones: Aromatic aldoxime ethers react with unactivated arenes catalyzed by palladium complexes to give biologically active fluoren-9-ones (see scheme). Multiple C-H bond activation and an oxidative cyclization are involved in the reaction. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：14723 / 14726

页数：4

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