Pd-Catalyzed Multiple C-H Functionalization to Construct Biologically Active Compounds from Aryl Aldoxime Ethers with Arenes

被引：54
|
作者：
Thirunavukkarasu, Vedhagiri S. [1 ]
Cheng, Chien-Hong [1 ]
机构：
[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu 30013, Taiwan
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2011年 / 17卷 / 52期
关键词：
C?H activation; cyclization; fluorenone; oxime ether; palladium; CROSS-COUPLING REACTIONS; ONE-POT SYNTHESIS; ORTHO-ARYLATION; BOND FUNCTIONALIZATION; ELECTRON-DEFICIENT; UNACTIVATED ARENES; SODIUM PERSULFATE; ACTIVATION; FLUORENONES; DERIVATIVES;
D O I：
10.1002/chem.201102996
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Functional fluorenones: Aromatic aldoxime ethers react with unactivated arenes catalyzed by palladium complexes to give biologically active fluoren-9-ones (see scheme). Multiple C-H bond activation and an oxidative cyclization are involved in the reaction. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：14723 / 14726
页数：4
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