PROTEIN ENGINEERING Finding the best ligase

被引：1
|
作者：
Becker, Christian F. W. [1 ]
机构：
[1] Univ Vienna, Fac Chem, Inst Biol Chem, Vienna, Austria
来源：
NATURE CHEMICAL BIOLOGY | 2018年 / 14卷 / 01期
关键词：
D O I：
10.1038/nchembio.2533
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Modification of folded proteins at will, within any sequence context, remains an elusive goal. A proteome-wide screening approach has now identified a set of protein ligases that enables conjugation of peptides to almost any protein N terminus, overcoming longstanding limitations in protein engineering.
引用
收藏
页码：2 / 3
页数：2
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