Finding better protein engineering strategies

被引：0
|
作者：
Romas J Kazlauskas
Uwe T Bornscheuer
机构：
[1] Molecular Biology & Biophysics,Romas J. Kazlauskas is in the Biotechnology Institute and Department of Biochemistry
[2] University of Minnesota,Department of Biotechnology & Enzyme Catalysis
[3] St. Paul,undefined
[4] Minnesota,undefined
[5] USA,undefined
[6] Uwe T. Bornscheuer is in the Institute of Biochemistry,undefined
[7] Greifswald University,undefined
[8] Greifswald,undefined
[9] Germany.,undefined
来源：
Nature Chemical Biology | 2009年 / 5卷
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D O I：
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学科分类号：
摘要：
Protein improvement strategies today involve widely varying combinations of rational design with random mutagenesis and screening. To make further progress—defined as making subsequent protein engineering problems easier to solve—protein engineers must critically compare these strategies and eliminate less effective ones.
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页码：526 / 529
页数：3
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