Toxicity of acrylamide and evaluation of its exposure in baby foods

被引:46
|
作者
Erkekoglu, Pinar [1 ]
Baydar, Terken [1 ]
机构
[1] Hacettepe Univ, Fac Pharm, Dept Toxicol, TR-06100 Ankara, Turkey
关键词
Acrylamide; Baby food; Infant formulas; Toxicity; EPOXIDE METABOLITE GLYCIDAMIDE; PERIPHERAL NERVOUS-SYSTEM; TANDEM MASS-SPECTROMETRY; REPRODUCTIVE TOXICITY; ADDUCT FORMATION; DEVELOPMENTAL TOXICITY; HEMOGLOBIN ADDUCTS; GERMAN CHILDREN; DRINKING-WATER; DIETARY-INTAKE;
D O I
10.1017/S0954422410000211
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Contaminants are a vast subject area of food safety and quality and can be present in our food chain from raw materials to finished products. Acrylamide, an alpha,beta-unsaturated (conjugated) reactive molecule, can be detected as a contaminant in several foodstuffs including baby foods and infant formulas. It is anticipated that children will generally have intakes that are two to three times those of adults when expressed on a body-weight basis. Though exposure to acrylamide is inevitable, it is necessary to protect infant and children from high exposure. The present review focuses on the several adverse health effects of acrylamide including mutagenicity, genotoxicity, carcinogenicity, neurotoxicity and reproductive toxicity, and the possible outcomes of childhood exposure from baby foods and infant formulas.
引用
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页码:323 / 333
页数:11
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