Synthesis of New Diaryl(hetaryl)ethylphosphonic Acids

被引：0
|
作者：
Sadykova, Yu M. [1 ]
Zalaltdinova, A., V [2 ]
Smailov, A. K. [2 ]
Burilov, A. R. [1 ]
Pudovik, M. A. [1 ]
机构：
[1] Russian Acad Sci, Arbuzov Inst Organ & Phys Chem, Fed Res Ctr, Kazan Sci Ctr, Kazan 420088, Russia
[2] Kazan Natl Res Technol Univ, Kazan 420015, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2021年 / 91卷 / 07期
基金：
俄罗斯基础研究基金会;
关键词：
diaryl(hetaryl)ethylphosphonic acids; (2-ethoxyvinyl)phosphonic dichloride; 4-hydroxy-6methyl-2-pyrone; 4-hydroxycoumarin; thymol; carvacrol; MOTIF;
D O I：
10.1134/S1070363221070215
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An original, new method for the synthesis of previously unknown diaryl(hetaryl)ethylphosphonic acids containing pharmacophoric fragments was developed as a result of the acid-catalyzed reaction of (2-ethoxyvinyl)phosphonic dichloride with heterocyclic compounds such as 4-hydroxy-6-methyl-2-pyrone, 4-hydroxycoumarin, and also thymol and carvacrol containing a hydroxyl group. Composition and structure of all diaryl(hetaryl)ethylphosphonic acids were confirmed according to H-1, C-13 and P-31 NMR, IR spectroscopy, mass spectrometry and elemental analysis data.
引用
收藏
页码：1420 / 1423
页数：4
相关论文
共 50 条
  • [31] NEW METHOD FOR THE SYNTHESIS OF DIARYL-SUBSTITUTED CYCLOPROPANES
    GRANDBERG, II
    YAKUSHCHENKO, IK
    DMITRIEV, LB
    ZHURNAL ORGANICHESKOI KHIMII, 1979, 15 (01): : 89 - 95
  • [32] SYNTHESIS OF NEW 2,5-DIARYL SELENOPHENES
    PRIM, D
    JOSEPH, D
    KIRSCH, G
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 1994, 91 (1-4): : 137 - 143
  • [33] THE PATTERN OF MASS-SPECTROMETRIC FRAGMENTATION OF (QUINUCLIDYL-3)DIARYL(HETARYL)CARBINOLS
    KULESHOVA, EF
    ANISIMOVA, OS
    SHEINKER, YN
    MIKHLINA, EE
    ARBUZOVA, OR
    YAKHONTOV, LN
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1990, (08): : 1078 - 1082
  • [34] New Route for the Synthesis of Hetaryl-1,5-benzodiazepines: Part 2
    Ahmed, Abdelraheem M.
    Abdel-Ghany, H.
    Moustafa, H. M.
    Khodairy, A.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2019, 56 (02) : 464 - 469
  • [35] Diastereospecific synthesis of trans-2,3-diaryl-1-aminocyclopropanecarboxylic acids
    Pan, CX
    Su, GF
    Qin, JK
    ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 2005, 37 (03) : 239 - 246
  • [36] Synthesis of new aryl and hetaryl dibromides and diiodides, the monomers for preparation of polyarylene ethynylenes
    Rusanov, AL
    Keshtov, ML
    Begretov, MM
    Khotina, IA
    Mikitaev, AK
    RUSSIAN CHEMICAL BULLETIN, 1996, 45 (05) : 1169 - 1175
  • [37] Synthesis and spectral investigation of some new hetaryl-substituted hydroquinolinone derivatives
    Anil, Baris
    Ozokan, Kadri G.
    Kaban, Seniz
    Sahin, Ertan
    Kazaza, Cavit
    MAGNETIC RESONANCE IN CHEMISTRY, 2016, 54 (02) : 184 - 189
  • [38] Synthesis and structure of aryl(hetaryl)spiropyrrolidones
    V. M. Berestovitskaya
    I. A. Litvinov
    O. S. Vasil’eva
    A. A. Nikonorov
    E. S. Ostroglyadov
    D. B. Krivolapov
    Russian Chemical Bulletin, 2012, 61 : 1014 - 1023
  • [39] Hetaryl Thioketones: Synthesis and Selected Reactions
    Mloston, Grzegorz
    Urbaniak, Katarzyna
    Gebicki, Krzysztof
    Grzelak, Paulina
    Heimgartner, Heinz
    HETEROATOM CHEMISTRY, 2014, 25 (06) : 548 - 555
  • [40] Synthesis of peptidomimetics using Diaryl-β amino acids for the preparation of smart materials
    Romero, Dulce Alitzel Quintana
    Bucci, Raffaella
    Gul, Merve
    Madrigal, Maria del Mar Perez
    Gelmi, Maria Luisa
    Aleman, Carlos
    JOURNAL OF PEPTIDE SCIENCE, 2024, 30
12345