Synthesis of New Diaryl(hetaryl)ethylphosphonic Acids

被引：0
|
作者：
Sadykova, Yu M. [1 ]
Zalaltdinova, A., V [2 ]
Smailov, A. K. [2 ]
Burilov, A. R. [1 ]
Pudovik, M. A. [1 ]
机构：
[1] Russian Acad Sci, Arbuzov Inst Organ & Phys Chem, Fed Res Ctr, Kazan Sci Ctr, Kazan 420088, Russia
[2] Kazan Natl Res Technol Univ, Kazan 420015, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2021年 / 91卷 / 07期
基金：
俄罗斯基础研究基金会;
关键词：
diaryl(hetaryl)ethylphosphonic acids; (2-ethoxyvinyl)phosphonic dichloride; 4-hydroxy-6methyl-2-pyrone; 4-hydroxycoumarin; thymol; carvacrol; MOTIF;
D O I：
10.1134/S1070363221070215
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An original, new method for the synthesis of previously unknown diaryl(hetaryl)ethylphosphonic acids containing pharmacophoric fragments was developed as a result of the acid-catalyzed reaction of (2-ethoxyvinyl)phosphonic dichloride with heterocyclic compounds such as 4-hydroxy-6-methyl-2-pyrone, 4-hydroxycoumarin, and also thymol and carvacrol containing a hydroxyl group. Composition and structure of all diaryl(hetaryl)ethylphosphonic acids were confirmed according to H-1, C-13 and P-31 NMR, IR spectroscopy, mass spectrometry and elemental analysis data.
引用
收藏
页码：1420 / 1423
页数：4
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