Natural Products Containing the Nitrile Functional Group and Their Biological Activities

被引：29
|
作者：
Scotti, Camille [1 ,2 ]
Barlow, James W. [2 ]
机构：
[1] Univ Haute Alsace, Ecole Natl Super Chim Mulhouse, Mulhouse, France
[2] RCSI Univ Med & Hlth Sci, Dublin, Ireland
来源：
NATURAL PRODUCT COMMUNICATIONS | 2022年 / 17卷 / 05期
关键词：
nitriles; natural products; bioactivity; review; origins; CYANOGENIC GLYCOSIDES; HYDROXYNITRILE GLUCOSIDES; CHEMICAL-CONSTITUENTS; THAI TUNICATE; SEED OILS; A-C; SPONGE; LEAVES; METABOLITES; ALKALOIDS;
D O I：
10.1177/1934578X221099973
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The importance of nitriles as a key class of chemicals with applications across the sciences is widely appreciated. The natural world is an underappreciated source of chemically diverse nitriles. With this in mind, this review describes novel nitrile-containing molecules isolated from natural sources from 1998 to 2021, as well as a discussion of the biological activity of these compounds. This study gathers 192 molecules from varied origins across the plant, animal, and microbial worlds. Their biological activity is extremely diverse, with many potential medicinal applications.
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页数：24
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