Natural Products Containing the Nitrile Functional Group and Their Biological Activities

被引：29
|
作者：
Scotti, Camille [1 ,2 ]
Barlow, James W. [2 ]
机构：
[1] Univ Haute Alsace, Ecole Natl Super Chim Mulhouse, Mulhouse, France
[2] RCSI Univ Med & Hlth Sci, Dublin, Ireland
来源：
NATURAL PRODUCT COMMUNICATIONS | 2022年 / 17卷 / 05期
关键词：
nitriles; natural products; bioactivity; review; origins; CYANOGENIC GLYCOSIDES; HYDROXYNITRILE GLUCOSIDES; CHEMICAL-CONSTITUENTS; THAI TUNICATE; SEED OILS; A-C; SPONGE; LEAVES; METABOLITES; ALKALOIDS;
D O I：
10.1177/1934578X221099973
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The importance of nitriles as a key class of chemicals with applications across the sciences is widely appreciated. The natural world is an underappreciated source of chemically diverse nitriles. With this in mind, this review describes novel nitrile-containing molecules isolated from natural sources from 1998 to 2021, as well as a discussion of the biological activity of these compounds. This study gathers 192 molecules from varied origins across the plant, animal, and microbial worlds. Their biological activity is extremely diverse, with many potential medicinal applications.
引用
收藏
页数：24
相关论文
共 50 条
  • [41] Natural hydrazine-containing compounds: Biosynthesis, isolation, biological activities and synthesis
    Le Goff, Geraldine
    Ouazzani, Jamal
    BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 22 (23) : 6529 - 6544
  • [42] Synthesis, Structure and Biological Activities of Novel Triazole Compounds Containing Ester Group
    Yang, Shuang-Hua
    Zhai, Zhi-Wei
    Zhang, Shao-Wen
    ASIAN JOURNAL OF CHEMISTRY, 2014, 26 (03) : 883 - 886
  • [43] Synthesis and Biological Activities of Novel Pyrazole Oximes Containing Substituted Pyrimidine Group
    Dai, Hong
    Ye, Linyua
    Li, Yang
    Fang, Yuan
    Shi, Yujun
    Liang, Zhipeng
    Shi, Jian
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 37 (04) : 1020 - 1026
  • [44] Design, Synthesis and Biological Activities of Novel Analogues of Chlorantraniliprole Containing Heptafluoroisopropyl Group
    Feng Qi
    Liu Zhi-Li
    Wang Ming-Zhong
    Xiong Li-Xia
    Yu Shu-Jing
    Li Zheng-Ming
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2011, 32 (01): : 74 - 78
  • [45] Synthesis, structure and biological activities of novel triazole compounds containing thioamide group
    Liu, FQ
    Qin, YQ
    Xu, LZ
    Lu, LD
    Yang, XJ
    Wang, X
    CHINESE JOURNAL OF CHEMISTRY, 2005, 23 (07) : 881 - 884
  • [46] SYNTHESIS AND SOME PROPERTIES OF CYCLOHEXADIENEIRONTRICARBONYLS CONTAINING A NITRILE GROUP
    NAMETKIN, NS
    TYURIN, VD
    SLUPCZYNSKI, M
    POLISH JOURNAL OF CHEMISTRY, 1979, 53 (03) : 583 - 590
  • [47] Glycosylation and Activities of Natural Products
    Huang, Gangliang
    Lv, Meijiao
    Hu, Jinchuan
    Huang, Kunlin
    Xu, Hong
    MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2016, 16 (12) : 1013 - 1016
  • [48] Natural products with biological activity
    Goldstein, Mindy S.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U4294 - U4295
  • [49] Natural Products and Biological Activities of Plants from Genus Morus: 2011-2023
    Wang, Yan-Ao
    Liu, Chao
    Guo, Xu
    Zhang, Meng-Qi
    Sun, Shutao
    Sun, Jin-Yue
    Khan, Afsar
    Liu, Lu
    Chen, Ying-Ying
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2023, 23 (28) : 2640 - 2698
  • [50] The Bioactive Natural Products and Biological Activities of the Red Sea Soft Coral Sarcophyton: A Review
    Hussien, Taha A.
    Mohamed, Tarik A.
    RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES, 2015, 6 (04): : 1301 - 1319
12345