Syntheses and biological activities of novel benzotriazole compounds containing a thioamide group

被引：2

作者：

Xu Liang-zhong ^{[1
]}

Zhai Zhi-wei ^{[1
]}

Yu Guan-ping ^{[1
]}

Qin Yong-qi ^{[1
]}

Yang Ya-xun ^{[1
]}

机构：

[1] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China

来源：

CHEMICAL RESEARCH IN CHINESE UNIVERSITIES | 2006年 / 22卷 / 05期

关键词：

benzotriazole; thioamide; crystal structure; biological activities;

D O I：

10.1016/S1005-9040(06)60165-7

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(E)-2-(1H-Benzo[d] [1,2,3] triazol-1-yl)-3-(4-chlorophenyl)-3-hydroxy-N-phenylprop-2-enethioamide (compound 1) and (E)-2-(1H-benzo[d] [1, 2, 3] triazol-1-yl)-3-hydroxy-N, 3-diphenylprop-2-enethioamide (compound 2) were synthesized and their structures were confirmed by means of IR, MS, H-1 NMR, and elemental analysis. The structure of compound I was determined with single-crystal X-ray diffraction analysis. The results of the biological test show that the two compounds have a certain antifungal activity.

引用

页码：574 / 576

页数：3

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