Blocking CRMP2 SUMOylation reverses neuropathic pain

被引：44
|
作者：
Moutal, A. [1 ]
Dustrude, E. T. [1 ,4 ,5 ]
Largent-Milnes, T. M. [1 ]
Vanderah, T. W. [1 ,2 ]
Khanna, M. [1 ]
Khanna, R. [1 ,2 ,3 ]
机构：
[1] Univ Arizona, Coll Med, Dept Pharmacol, Tucson, AZ 85724 USA
[2] Univ Arizona, Dept Anesthesiol, Coll Med, Tucson, AZ 85721 USA
[3] Univ Arizona, Dept Neurosci, Coll Med, Grad Interdisciplinary Program, Tucson, AZ 85721 USA
[4] Indiana Univ Sch Med, Dept Psychiat, Inst Psychiat Res, Indianapolis, IN 46202 USA
[5] Indiana Univ Sch Med, Stark Neurosci Res Inst, Neurosci Res Bldg,320W 15th St,Room 314, Indianapolis, IN 46202 USA
来源：
MOLECULAR PSYCHIATRY | 2018年 / 23卷 / 11期
关键词：
SCHIZOPHRENIA; GENE;
D O I：
10.1038/mp.2017.117
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：2119 / 2121
页数：3
相关论文
共 50 条
  • [21] CRMP1 and CRMP2 have synergistic but distinct roles in dendritic development
    Makihara, Hiroko
    Nakai, Shiori
    Ohkubo, Wataru
    Yamashita, Naoya
    Nakamura, Fumio
    Kiyonari, Hiroshi
    Shioi, Go
    Jitsuki-Takahashi, Aoi
    Nakamura, Haruko
    Tanaka, Fumiaki
    Akase, Tomoko
    Kolattukudy, Pappachan
    Goshima, Yoshio
    GENES TO CELLS, 2016, 21 (09) : 994 - 1005
  • [22] CRMP2 Phosphorylation Drives Glioblastoma Cell Proliferation
    Aubin Moutal
    Lex Salas Villa
    Seul Ki Yeon
    Kyle T. Householder
    Ki Duk Park
    Rachael W. Sirianni
    Rajesh Khanna
    Molecular Neurobiology, 2018, 55 : 4403 - 4416
  • [23] Phosphorylated CRMP2 Regulates Spinal Nociceptive Neurotransmission
    Jie Yu
    Aubin Moutal
    Angie Dorame
    Shreya S. Bellampalli
    Aude Chefdeville
    Iori Kanazawa
    Nancy Y. N. Pham
    Ki Duk Park
    Jill M. Weimer
    Rajesh Khanna
    Molecular Neurobiology, 2019, 56 : 5241 - 5255
  • [24] A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors
    Francois-Moutal, Liberty
    Wang, Yue
    Moutal, Aubin
    Cottier, Karissa E.
    Melemedjian, Ohannes K.
    Yang, Xiaofang
    Wang, Yuying
    Ju, Weina
    Largent-Milnes, Tally M.
    Khanna, May
    Vanderah, Todd W.
    Khanna, Rajesh
    PAIN, 2015, 156 (07) : 1247 - 1264
  • [25] CRMP2 Phosphorylation Drives Glioblastoma Cell Proliferation
    Moutal, Aubin
    Villa, Lex Salas
    Yeon, Seul Ki
    Householder, Kyle T.
    Park, Ki Duk
    Sirianni, Rachael W.
    Khanna, Rajesh
    MOLECULAR NEUROBIOLOGY, 2018, 55 (05) : 4403 - 4416
  • [26] Phosphorylated CRMP2 Regulates Spinal Nociceptive Neurotransmission
    Yu, Jie
    Moutal, Aubin
    Dorame, Angie
    Bellampalli, Shreya S.
    Chefdeville, Aude
    Kanazawa, Iori
    Pham, Nancy Y. N.
    Park, Ki Duk
    Weimer, Jill M.
    Khanna, Rajesh
    MOLECULAR NEUROBIOLOGY, 2019, 56 (07) : 5241 - 5255
  • [27] Tat-Collapsin Response Mediator Protein 2 (CRMP2) Increases the Survival of Neurons After NMDA Excitotoxity by Reducing the Cleavage of CRMP2
    Yin, Yanling
    Wang, Yansong
    Chen, Lumian
    Han, Song
    Zhao, Li
    Luo, Yanlin
    Li, Junfa
    NEUROCHEMICAL RESEARCH, 2013, 38 (10) : 2095 - 2104
  • [28] Tat-Collapsin Response Mediator Protein 2 (CRMP2) Increases the Survival of Neurons After NMDA Excitotoxity by Reducing the Cleavage of CRMP2
    Yanling Yin
    Yansong Wang
    Lumian Chen
    Song Han
    Li Zhao
    Yanlin Luo
    Junfa Li
    Neurochemical Research, 2013, 38 : 2095 - 2104
  • [29] CRMP2 Contributes to Dendritic Arbor Pathology in Schizophrenia
    Konopaske, Glenn
    Tobe, Brian
    Snyder, Evan
    Benes, Francine
    Coyle, Joseph
    NEUROPSYCHOPHARMACOLOGY, 2016, 41 : S406 - S406
  • [30] Regulation of axon pruning of mossy fiber projection in hippocampus by CRMP2 and CRMP4
    Nakanishi, Yurika
    Akinaga, Satoshi
    Osawa, Koki
    Suzuki, Natusmi
    Sugeno, Ayaka
    Kolattukudy, Papachan
    Goshima, Yoshio
    Ohshima, Toshio
    DEVELOPMENTAL NEUROBIOLOGY, 2022, 82 (01) : 138 - 146
12345