Synthesis of oligonucleotide building blocks of 2′-deoxyguanosine bearing a C8-arylamine modification

被引：3

作者：

Gräsl, S ^{[1
]}

Meier, C ^{[1
]}

机构：

[1] Univ Hamburg, Inst Organ Chem, D-20146 Hamburg, Germany

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2003年 / 22卷 / 5-8期

关键词：

arylamine-adducts; palladium-catalyzed; cross-coupling;

D O I：

10.1081/NCN-120022751

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

C8-Arylamine-dG adducts were synthesized by palladium-catalyzed cross-coupling reactions. The corresponding 5'-O-DMTr-3'-O-phosphoramidite-C8-arylamine-dG adducts were synthesized as potential building blocks for the automated synthesis of site-specifically modified oligonucleotides.

引用

页码：1119 / 1121

页数：3

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