Synthesis of oligonucleotide building blocks of 2′-deoxyguanosine bearing a C8-arylamine modification

被引：3
|
作者：
Gräsl, S [1 ]
Meier, C [1 ]
机构：
[1] Univ Hamburg, Inst Organ Chem, D-20146 Hamburg, Germany
来源：
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2003年 / 22卷 / 5-8期
关键词：
arylamine-adducts; palladium-catalyzed; cross-coupling;
D O I：
10.1081/NCN-120022751
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
C8-Arylamine-dG adducts were synthesized by palladium-catalyzed cross-coupling reactions. The corresponding 5'-O-DMTr-3'-O-phosphoramidite-C8-arylamine-dG adducts were synthesized as potential building blocks for the automated synthesis of site-specifically modified oligonucleotides.
引用
收藏
页码：1119 / 1121
页数：3
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