Fed-batch fermentation of Lactobacillus lactis for hyper-production of L-lactic acid

被引:74
|
作者
Bai, DM
Wei, Q
Yan, ZH
Zhao, XM [1 ]
Li, XG
Xu, SM
机构
[1] Tianjin Univ, Sch Chem Engn & Technol, Dept Biochem Engn, Tianjin 300072, Peoples R China
[2] Tianjin Univ, Natl Engn Res Ctr Distillat Technol, Tianjin 300072, Peoples R China
关键词
fed-batch; fermentation; glucose feeding; Lactobacillus lactis; L-lactic acid;
D O I
10.1023/A:1026276925649
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
A fed-batch fermentation of Lactobacillus lactis to produce L-lactic acid was developed in which the residual glucose concentration in the culture was used to control a continuous feeding strategy. Up to 210 g L-lactic acid l(-1) (97% yield) was obtained. The maximal dry cell was 2.7 g l(-1) and the average L-lactic acid productivity was 2.2 g l(-1) h(-1).
引用
收藏
页码:1833 / 1835
页数:3
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