Fed-batch fermentation of Lactobacillus lactis for hyper-production of L-lactic acid

被引：74
|
作者：
Bai, DM
Wei, Q
Yan, ZH
Zhao, XM [1 ]
Li, XG
Xu, SM
机构：
[1] Tianjin Univ, Sch Chem Engn & Technol, Dept Biochem Engn, Tianjin 300072, Peoples R China
[2] Tianjin Univ, Natl Engn Res Ctr Distillat Technol, Tianjin 300072, Peoples R China
来源：
BIOTECHNOLOGY LETTERS | 2003年 / 25卷 / 21期
关键词：
fed-batch; fermentation; glucose feeding; Lactobacillus lactis; L-lactic acid;
D O I：
10.1023/A:1026276925649
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
A fed-batch fermentation of Lactobacillus lactis to produce L-lactic acid was developed in which the residual glucose concentration in the culture was used to control a continuous feeding strategy. Up to 210 g L-lactic acid l(-1) (97% yield) was obtained. The maximal dry cell was 2.7 g l(-1) and the average L-lactic acid productivity was 2.2 g l(-1) h(-1).
引用
收藏
页码：1833 / 1835
页数：3
相关论文
共 50 条
  • [31] PRODUCTION OF L-LACTIC ACID WITH IMMOBILIZED LACTOBACILLUS-DELBRUECKII
    STENROOS, SL
    LINKO, YY
    LINKO, P
    BIOTECHNOLOGY LETTERS, 1982, 4 (03) : 159 - 164
  • [32] GLYCEROL PRODUCTION BY FERMENTATION - A FED-BATCH APPROACH
    VIJAIKISHORE, P
    KARANTH, NG
    BIOTECHNOLOGY AND BIOENGINEERING, 1987, 30 (02) : 325 - 328
  • [33] Insight into evolutionary optimization approach of batch and fed-batch fermenters for lactic acid production
    Gujarathi, Ashish M.
    Patel, Swaprabha P.
    Al Siyabi, Badria
    DIGITAL CHEMICAL ENGINEERING, 2023, 8
  • [34] The use of date waste for lactic acid production by a fed-batch culture using Lactobacillus casei subsp rhamnosus
    Nancib, Aicha
    Nancib, Nabil
    Boubendir, Abdelhafid
    Boudrant, Joseph
    BRAZILIAN JOURNAL OF MICROBIOLOGY, 2015, 46 (03) : 893 - 902
  • [35] Bacteriocin production with Lactobacillus amylovorus DCE 471 is improved and stabilized by fed-batch fermentation
    Callewaert, R
    De Vuyst, L
    APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2000, 66 (02) : 606 - 613
  • [36] Mathematical modelling of fed-batch fermentation processes for amino acid production
    Georgiev, T
    Ratkov, A
    Tzonkov, S
    MATHEMATICS AND COMPUTERS IN SIMULATION, 1997, 44 (03) : 271 - 285
  • [37] Mathematical modelling of fed-batch fermentation processes for amino acid production
    Technical Univ, Sofia, Bulgaria
    Math Comput Simul, 3 (271-285):
  • [38] Greener L-lactic acid production through in situ extractive fermentation by an acid-tolerant Lactobacillus strain
    Mamata Singhvi
    Takeshi Zendo
    Digambar Gokhale
    Kenji Sonomoto
    Applied Microbiology and Biotechnology, 2018, 102 : 6425 - 6435
  • [39] Production of gamma-aminobutyric acid by Lactobacillus brevis NCL912 using fed-batch fermentation
    Haixing Li
    Ting Qiu
    Guidong Huang
    Yusheng Cao
    Microbial Cell Factories, 9
  • [40] Production of polysialic acid from fed-batch fermentation with pH control
    Zhan, XB
    Zhu, L
    Wu, JR
    Zhen, ZY
    Jia, W
    BIOCHEMICAL ENGINEERING JOURNAL, 2002, 11 (2-3) : 201 - 204
12345