Preclinical identification of AZD7762, a novel, potent and selective inhibitor of Checkpoint kinases

被引：0

作者：

Ashwell, Susan ^{[1
]}

Caleb, Benjamin L. ^{[1
]}

Deng, Chun ^{[1
]}

Green, Stephen ^{[2
]}

Grondine, Michael R. ^{[1
]}

Haye, Heather R. ^{[2
]}

Horn, Candice L. ^{[1
]}

Janetka, James W.

Liu, Dongfang ^{[1
]}

Mouchet, Elizabeth ^{[2
]}

Ready, Shannon ^{[1
]}

Rosenthal, Judith L. ^{[1
]}

Queva, Christophe ^{[1
]}

Taylor, Karen J. ^{[2
]}

Sheehy, Adam M. ^{[1
]}

Walker, Graeme E. ^{[2
]}

White, Anne M. ^{[2
]}

Zabludoff, Sonya D. ^{[1
]}

机构：

[1] AstraZeneca, Waltham, MA USA

[2] AstraZeneca, Macclesfield, Cheshire, England

来源：

MOLECULAR CANCER THERAPEUTICS | 2007年 / 6卷 / 12期

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：3411S / 3411S

页数：1

共 50 条

[1] Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and bone remodeling
Wang, Luqi
Wang, Yue
Chen, Andy
Jalali, Aydin
Liu, Shengzhi
Guo, Yunxia
Na, Sungsoo
Nakshatri, Harikrishna
Li, Bai-Yan
Yokota, Hiroki
INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 53 (03) : 1001 - 1012
[2] AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies
Zabludoff, Sonya D.
Deng, Chun
Grondine, Michael R.
Sheehy, Adam M.
Ashwell, Susan
Caleb, Benjamin L.
Green, Stephen
Haye, Heather R.
Horn, Candice L.
Janetka, James W.
Liu, Dongfang
Mouchet, Elizabeth
Ready, Shannon
Rosenthal, Judith L.
Queva, Christophe
Schwartz, Gary K.
Taylor, Karen J.
Tse, Archie N.
Walker, Graeme E.
White, Anne M.
MOLECULAR CANCER THERAPEUTICS, 2008, 7 (09) : 2955 - 2966
[3] In vitro and In vivo Radiation Sensitization of Human Tumor Cells by a Novel Checkpoint Kinase Inhibitor, AZD7762
Mitchell, James B.
Choudhuri, Rajani
Fabre, Kristin
Sowers, Anastasia L.
Citrin, Deborah
Zabludoff, Sonya D.
Cook, John A.
CLINICAL CANCER RESEARCH, 2010, 16 (07) : 2076 - 2084
[4] Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine
Makoto Isono
Michèle J. Hoffmann
Maria Pinkerneil
Akinori Sato
Martin Michaelis
Jindrich Cinatl
Günter Niegisch
Wolfgang A. Schulz
Journal of Experimental & Clinical Cancer Research, 36
[5] Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine
Isono, Makoto
Hoffmann, Michele J.
Pinkerneil, Maria
Sato, Akinori
Michaelis, Martin
Cinatl, Jindrich, Jr.
Niegisch, Guenter
Schulz, Wolfgang A.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2017, 36 : 1 - 12
[6] Checkpoint Kinase Inhibitor AZD7762 Overcomes Cisplatin Resistance in Clear Cell Carcinoma of the Ovary
Itamochi, Hiroaki
Nishimura, Mayumi
Oumi, Nao
Kato, Misaki
Oishi, Tetsuro
Shimada, Muneaki
Sato, Shinya
Naniwa, Jun
Sato, Seiya
Kudoh, Akiko
Kigawa, Junzo
Harada, Tasuku
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2014, 24 (01) : 61 - 69
[7] Checkpoint kinase inhibitor AZD7762 enhance cisplatin-induced apoptosis in osteosarcoma cells
Zhu, Jian
Zou, Hanhui
Yu, Wei
Huang, Yuluan
Liu, Bing
Li, Tao
Liang, Chengzhen
Tao, Huimin
CANCER CELL INTERNATIONAL, 2019, 19 (1)
[8] Checkpoint kinase inhibitor AZD7762 enhance cisplatin-induced apoptosis in osteosarcoma cells
Jian Zhu
Hanhui Zou
Wei Yu
Yuluan Huang
Bing Liu
Tao Li
Chengzhen Liang
Huimin Tao
Cancer Cell International, 19
[9] Preclinical optimization of the Chk1/2 inhibitor AZD7762 in combination with gemcitabine in pancreatic cancer
Parsels, Leslie A.
Morgan, Meredith A.
Tanska, Dania M.
Parsels, Joshua D.
Davis, Mary A.
Hassan, Maria C.
Arumugarajah, Sankari
Hylander-Gans, Linda
Morosini, Deborah
Zhao, Lili
Simeone, Diane M.
Canman, Christine E.
Normolle, Daniel P.
Zabludoff, Sonya D.
Lawrence, Theodore S.
Maybaum, Jonathan
CANCER RESEARCH, 2010, 70
[10] Potentiation of the Novel Topoisomerase I Inhibitor Indenoisoquinoline LMP-400 by the Cell Checkpoint and Chk1-Chk2 Inhibitor AZD7762
Aris, Sheena M.
Pommier, Yves
CANCER RESEARCH, 2012, 72 (04) : 979 - 989

← 1 2 3 4 5 →