Synthesis and structure of N-(2-(1-adamantyl)-2-hydroxyethyl)cytisine diastereomers

被引：2
|
作者：
Shishkin, D. V. [1 ]
Mukhamed'yarova, E. R.
Baibulatova, N. Z.
Dokichev, V. A.
Tomilov, Yu. V.
机构：
[1] Russian Acad Sci, Inst Organ Chem, Ufa Sci Ctr, Ufa, Russia
[2] Russian Acad Sci, ND Zelinskii Organ Chem Inst, Moscow, Russia
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2007年 / 43卷 / 03期
关键词：
synthesis; cytisine derivatives; diastereomers; 15(R)- and 15(S)-N-(2-(1-adamantyl)-2-hydroxyethyl)cytisine; x-ray structure analysis; PMR; C-13; NMR;
D O I：
10.1007/s10600-007-0108-z
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Diastereomers of N-(2-(1-adamantyl)-2-hydroxyethyl)cytisine were synthesized by reduction of N-(2-(1-adamantyl)-2-oxoethyl)cytisine with NaBH4. Their structures were established using x-ray structure analysis.
引用
收藏
页码：293 / 297
页数：5
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