Label-free detection of DNA hybridization with Au/SiO2/Si diodes and poly-Si TFTs

被引：0
|
作者：
Estrela, P [1 ]
Stewart, AG [1 ]
Migliorato, P [1 ]
Maeda, H [1 ]
机构：
[1] Univ Cambridge, Dept Engn, Cambridge CB2 1PZ, England
来源：
IEEE INTERNATIONAL ELECTRON DEVICES MEETING 2004, TECHNICAL DIGEST | 2004年
关键词：
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
Label-free electrical detection of DNA hybridization has been achieved by employing Au/SiO2/Si MOS diodes and Poly-Si TFTs. The detection is based on the modulation of the gate voltage associated with the increased negative charge on the gate upon hybridization. The method can be applied to other bio-reactions that result in a modification of surface dipoles.
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页码：1009 / 1012
页数：4
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