Label-free detection of DNA hybridization with Au/SiO2/Si diodes and poly-Si TFTs

被引：0

作者：

Estrela, P ^{[1
]}

Stewart, AG ^{[1
]}

Migliorato, P ^{[1
]}

Maeda, H ^{[1
]}

机构：

[1] Univ Cambridge, Dept Engn, Cambridge CB2 1PZ, England

来源：

IEEE INTERNATIONAL ELECTRON DEVICES MEETING 2004, TECHNICAL DIGEST | 2004年

关键词：

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Label-free electrical detection of DNA hybridization has been achieved by employing Au/SiO2/Si MOS diodes and Poly-Si TFTs. The detection is based on the modulation of the gate voltage associated with the increased negative charge on the gate upon hybridization. The method can be applied to other bio-reactions that result in a modification of surface dipoles.

引用

页码：1009 / 1012

页数：4

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