The Galvanizing of Mycobacterium tuberculosis: An Antimicrobial Mechanism

被引：8
|
作者：
Russell, David G. [1 ]
机构：
[1] Cornell Univ, Coll Vet Med, Dept Microbiol & Immunol, Ithaca, NY 14850 USA
来源：
CELL HOST & MICROBE | 2011年 / 10卷 / 03期
关键词：
CONTAINING PHAGOSOMES; GENE-EXPRESSION; EARLY ENDOSOMES; CELLS; IONS;
D O I：
10.1016/j.chom.2011.08.008
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Evolving under constant threat from invading microbes, macrophages have acquired multiple means of killing bacteria. In this issue of Cell Host & Microbe, Botella and colleagues (Botella et al., 2011) describe a novel antimicrobial mechanism based on elevated levels of intraphagosomal Zn(2+) and the corresponding induction of bacterial genes to ameliorate this host-derived stress.
引用
收藏
页码：181 / 183
页数：3
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