The Galvanizing of Mycobacterium tuberculosis: An Antimicrobial Mechanism

被引：8
|
作者：
Russell, David G. [1 ]
机构：
[1] Cornell Univ, Coll Vet Med, Dept Microbiol & Immunol, Ithaca, NY 14850 USA
来源：
CELL HOST & MICROBE | 2011年 / 10卷 / 03期
关键词：
CONTAINING PHAGOSOMES; GENE-EXPRESSION; EARLY ENDOSOMES; CELLS; IONS;
D O I：
10.1016/j.chom.2011.08.008
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Evolving under constant threat from invading microbes, macrophages have acquired multiple means of killing bacteria. In this issue of Cell Host & Microbe, Botella and colleagues (Botella et al., 2011) describe a novel antimicrobial mechanism based on elevated levels of intraphagosomal Zn(2+) and the corresponding induction of bacterial genes to ameliorate this host-derived stress.
引用
收藏
页码：181 / 183
页数：3
相关论文
共 50 条
  • [41] The Mechanism of Acetyl Transfer Catalyzed by Mycobacterium tuberculosis GImU
    Craggs, Peter D.
    Mouilleron, Stephane
    Rejzek, Martin
    de Chiara, Cesira
    Young, Robert J.
    Field, Robert A.
    Argyrou, Argyrides
    de Carvalho, Luiz Pedro S.
    BIOCHEMISTRY, 2018, 57 (24) : 3387 - 3401
  • [42] MECHANISM FOR PYRIDOXAL NEUTRALIZATION OF ISONIAZID ACTION ON MYCOBACTERIUM TUBERCULOSIS
    BEGGS, WH
    JENNE, JW
    JOURNAL OF BACTERIOLOGY, 1967, 94 (04) : 793 - &
  • [43] DYNAMICS AND MECHANISM OF MYCOBACTERIUM TUBERCULOSIS CYP51
    Hackett, John C.
    DRUG METABOLISM REVIEWS, 2007, 39 : 194 - 194
  • [44] In vitro activity of 12 antimicrobial peptides against Mycobacterium tuberculosis and Mycobacterium avium clinical isolates
    Portell-Buj, Elena
    Vergara, Andrea
    Alejo, Izaskun
    Lopez-Gavin, Alexandre
    Rosa Monte, Maria
    San Nicolas, Lorena
    Gonzalez-Martin, Julian
    Tudo, Griselda
    JOURNAL OF MEDICAL MICROBIOLOGY, 2019, 68 (02) : 211 - 215
  • [45] Structural insights into the regulation mechanism of Mycobacterium tuberculosis MftR
    Peng, Fei
    Ke, Zunhui
    Jin, Haoruo
    Wang, Wei
    Zhang, Haoran
    Li, Yan
    FASEB JOURNAL, 2024, 38 (11):
  • [46] Gene Regulatory Mechanism of Mycobacterium Tuberculosis during Dormancy
    Liu, Yiduo
    Li, Han
    Dai, Dejia
    He, Jiakang
    Liang, Zhengmin
    CURRENT ISSUES IN MOLECULAR BIOLOGY, 2024, 46 (06) : 5825 - 5844
  • [47] Catalytic Mechanism of Mycobacterium tuberculosis Methionine Sulfoxide Reductase A
    Sastre, Santiago
    Manta, Bruno
    Semelak, Jonathan A.
    Estrin, Dario
    Trujillo, Madia
    Radi, Rafael
    Zeida, Ari
    BIOCHEMISTRY, 2024, 63 (04) : 533 - 544
  • [48] Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis
    Vergne, I
    Chua, J
    Lee, HH
    Lucas, M
    Belisle, J
    Deretic, V
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (11) : 4033 - 4038
  • [49] Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
    Favrot, Lorenza
    Grzegorzewicz, Anna E.
    Lajiness, Daniel H.
    Marvin, Rachel K.
    Boucau, Julie
    Isailovic, Dragan
    Jackson, Mary
    Ronning, Donald R.
    NATURE COMMUNICATIONS, 2013, 4
  • [50] Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
    Lorenza Favrot
    Anna E. Grzegorzewicz
    Daniel H. Lajiness
    Rachel K. Marvin
    Julie Boucau
    Dragan Isailovic
    Mary Jackson
    Donald R. Ronning
    Nature Communications, 4
12345