In vitro activities of the ketolide HMR 3647 against recent gram-positive clinical isolates and Haemophilus influenzae

被引：58
|
作者：
Barry, AL [1 ]
Fuchs, PC [1 ]
Brown, SD [1 ]
机构：
[1] Inst Clin Microbiol, Wilsonville, OR 97070 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1998年 / 42卷 / 08期
关键词：
D O I：
10.1128/AAC.42.8.2138
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The ketolide HMR 3647 (previously RU 66647) was evaluated against 2,563 recent clinical isolates of gram-positive pathogens and 200 Haemophilus influenzae isolates. HMR 3647 was active against macrolide-resistant streptococci, including pneumococci, but was not active against macrolide- or lincosamide-resistant staphylococci. Against H. influenzae, the potency of HMR 3647 was similar to that of azithromycin.
引用
下载
收藏
页码：2138 / 2140
页数：3
相关论文
共 50 条
  • [21] Comparative in vitro activity of moxifloxacin against Gram-positive clinical isolates
    Hoogkamp-Korstanje, JAA
    Roelofs-Willemse, J
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2000, 45 (01) : 31 - 39
  • [22] In Vitro Activity of Novel Rifamycins against Gram-positive Clinical Isolates
    Christopher K Murphy
    Elena Karginova
    Dan Sahm
    David M Rothstein
    The Journal of Antibiotics, 2007, 60 : 572 - 576
  • [23] In vitro activity of novel rifamycins against gram-positive clinical isolates
    Murphy, Christopher K.
    Karginova, Elena
    Sahm, Dan
    Rothstein, David M.
    JOURNAL OF ANTIBIOTICS, 2007, 60 (09): : 572 - 576
  • [24] Comparative antimicrobial activity and kill-curve investigations of novel ketolide antimicrobial agents (HMR 3004 and HMR 3647) tested against Haemophilus influenzae and Moraxella catarrhalis strains
    Biedenbach, DJ
    Barrett, MS
    Jones, RN
    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 1998, 31 (02) : 349 - 353
  • [25] In Vitro Activities of Three New Dihydrofolate Reductase Inhibitors against Clinical Isolates of Gram-Positive Bacteria
    Bowker, Karen E.
    Caspers, Patrick
    Gaucher, Berengere
    MacGowan, Alasdair P.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (11) : 4949 - 4952
  • [26] Potency and Bactericidal Activity of Iclaprim against Recent Clinical Gram-Positive Isolates
    Sader, Helio S.
    Fritsche, Thomas R.
    Jones, Ronald N.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (05) : 2171 - 2175
  • [27] In vitro activity of linezolid against multiply resistant Gram-positive clinical isolates
    Cercenado, E
    García-Garrote, F
    Bouza, E
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2001, 47 (01) : 77 - 81
  • [28] Comparative in vitro antibacterial activity of ozenoxacin against Gram-positive clinical isolates
    Canton, Rafael
    Morrissey, Ian
    Vila, Jordi
    Tato, Marta
    Garcia-Castillo, Maria
    Lopez, Yuly
    Gargallo-Viola, Domingo
    Zsolt, Ilonka
    FUTURE MICROBIOLOGY, 2018, 13 (06) : 3 - 19
  • [29] The in vitro activity of daptomycin against 514 Gram-positive aerobic clinical isolates
    King, A
    Phillips, I
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2001, 48 (02) : 219 - 223
  • [30] Comparative antimicrobial activity of ABT-773, a novel ketolide, tested against drug-resistant Gram-positive cocci and Haemophilus influenzae
    Rospide, MF
    Biedenbach, DJ
    Jones, RN
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2001, 17 (06) : 451 - 455
12345