In vitro activity of linezolid against multiply resistant Gram-positive clinical isolates

被引：54
|
作者：
Cercenado, E [1 ]
García-Garrote, F [1 ]
Bouza, E [1 ]
机构：
[1] Hosp Gen Univ Gregorio Maranon, Microbiol Serv, Madrid 28007, Spain
来源：
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2001年 / 47卷 / 01期
关键词：
D O I：
10.1093/jac/47.1.77
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The in vitro activity of the oxazolidinone linezolid was compared with the activities of vancomycin and telcoplanin against 450 Gram-positive clinical isolates, including a variety of multiply resistant strains. Linezolid inhibited all microorganisms tested at less than or equal to4 mg/L, including methicillin- and teicoplanin-resistant staphylococci, glycopeptide-resistant enterococci, penicillin- and multiply resistant pneumococci and viridans streptococci, and erythromycin-resistant beta -haemolytic streptococci. The MIC90 of linezolid for all isolates was 2 mg/L.
引用
收藏
页码：77 / 81
页数：5
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