In vitro activities of the ketolide HMR 3647 against recent gram-positive clinical isolates and Haemophilus influenzae

被引:58
|
作者
Barry, AL [1 ]
Fuchs, PC [1 ]
Brown, SD [1 ]
机构
[1] Inst Clin Microbiol, Wilsonville, OR 97070 USA
关键词
D O I
10.1128/AAC.42.8.2138
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The ketolide HMR 3647 (previously RU 66647) was evaluated against 2,563 recent clinical isolates of gram-positive pathogens and 200 Haemophilus influenzae isolates. HMR 3647 was active against macrolide-resistant streptococci, including pneumococci, but was not active against macrolide- or lincosamide-resistant staphylococci. Against H. influenzae, the potency of HMR 3647 was similar to that of azithromycin.
引用
下载
收藏
页码:2138 / 2140
页数:3
相关论文
共 50 条
  • [41] Relative potency of telithromycin, azithromycin and erythromycin against recent clinical isolates of gram-positive cocci
    Barry A.L.
    Fuchs P.C.
    Brown S.D.
    European Journal of Clinical Microbiology and Infectious Diseases, 2001, 20 (7): : 494 - 497
  • [42] Comparative In Vitro Activity of Trovafloxacin Against Gram-Positive and Gram-Negative Clinical Isolates from Argentina
    Adriana Sucari
    D. Stepanik
    J. M. Casellas
    G. Tomé
    L. Clara
    M. Marín
    A. Rossi
    M. Galas
    J. Smayevsky
    L. Dufranc
    H. Lorenzo
    L. de Vedia
    H. López
    Drugs, 1999, 58 : 195 - 199
  • [43] Comparative in vitro activity of trovafloxacin against Gram-positive and Gram-negative clinical isolates from Argentina
    Sucari, A
    Stepanik, D
    Casellas, JM
    Tomé, G
    Clara, L
    Marín, M
    Rossi, A
    Galas, M
    Smayevsky, J
    Dufranc, L
    Lorenzo, H
    de Vedia, L
    López, H
    DRUGS, 1999, 58 (Suppl 2) : 195 - 199
  • [44] In vitro activity of quinupristin/dalfopristin against clinical isolates of common Gram-positive bacteria in Taiwan
    Chang, SC
    Fang, CT
    Hsueh, PR
    Luh, KT
    Hsieh, WC
    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 1999, 33 (04) : 299 - 303
  • [45] In vitro activity of quinupristin/dalfopristin, RP59500, against gram-positive clinical isolates
    Qadri, SMH
    Ueno, Y
    AbuMostafa, FM
    Halim, M
    CHEMOTHERAPY, 1997, 43 (02) : 94 - 99
  • [46] In vitro activity of daptomycin against gram-positive European clinical isolates with defined resistance determinants
    Fluit, AC
    Schmitz, FJ
    Verhoef, J
    Milatovic, D
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (03) : 1007 - 1011
  • [47] Telavancin activity in vitro tested against a worldwide collection of Gram-positive clinical isolates (2014)
    Duncan, Leonard R.
    Sader, Helio S.
    Smart, Jennifer I.
    Flamm, Robert K.
    Mendes, Rodrigo E.
    JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE, 2017, 10 : 271 - 276
  • [48] Comparative in vitro activity of nine antistaphylococcal agents against 275 recent isolates of Gram-positive cocci
    Ravaoarinoro, M
    Therrien, C
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 1996, 7 (03) : 167 - 170
  • [49] In vitro activity of the new ketolide HMR3647 in comparison with those of macrolides and pristinamycins against Enterococcus spp.
    Torres, C
    Zarazaga, M
    Tenorio, C
    Portillo, A
    Saenz, Y
    Ruiz, F
    Baquero, F
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1998, 42 (12) : 3279 - 3281
  • [50] COMPARATIVE INVITRO ACTIVITY OF AZITHROMYCIN AND ERYTHROMYCIN AGAINST GRAM-POSITIVE COCCI, HAEMOPHILUS-INFLUENZAE AND ANAEROBES
    MASKELL, JP
    SEFTON, AM
    WILLIAMS, JD
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1990, 25 : 19 - 24